SCHEMBL1133083

SCHEMBL1133083

O=C(Oc1ccccc1)c1ccccc1Cl

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.63
ALOX15 P16050 1/20 0.63
HSD17B10 Q99714 1/20 0.63
KMT2A Q03164 6/20 0.60
SMN1; SMN2 Q16637 2/20 0.60
POLB P06746 2/20 0.60
MAPT P10636 5/20 0.59
KDM4E B2RXH2 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
MEN1 O00255 3/20 0.58
PKM P14618 2/20 0.58
ESR1 P03372 2/20 0.58
ESR2 Q92731 2/20 0.58
ALDH1A1 P00352 2/20 0.57
NPC1 O15118 2/20 0.56
RAB9A P51151 2/20 0.56
GAA P10253 1/20 0.56
NFKB1 P19838 1/20 0.56
NFKB2 Q00653 1/20 0.56
RELA Q04206 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24804992 0.94 KMT2A (0.67) HPGDALOX15HSD17B10KMT2ASMN1; SMN2
SCHEMBL24805001 0.88 KMT2A (0.63) HPGDALOX15HSD17B10KMT2ASMN1; SMN2
SCHEMBL8198021 0.85 KMT2A (0.58) HPGDALOX15HSD17B10KMT2ASMN1; SMN2
SCHEMBL9563122 0.85 PTK2B (0.60) HPGDKMT2ASMN1; SMN2POLBMAPT
SCHEMBL5685731 0.85 KMT2A (0.55) HPGDALOX15HSD17B10KMT2ASMN1; SMN2
SCHEMBL29437924 0.85 HSD17B10 (0.76) HPGDALOX15HSD17B10KMT2ASMN1; SMN2
SCHEMBL69868 0.85 HSD17B10 (0.76) HPGDALOX15HSD17B10KMT2ASMN1; SMN2
Chlorobenzene SCHEMBL11761343 0.84 HSD17B10 (0.63) HPGDALOX15HSD17B10KMT2ASMN1; SMN2
SCHEMBL28868709 0.83 HSD17B10 (0.68) HPGDALOX15HSD17B10KMT2ASMN1; SMN2
Chloromethane SCHEMBL27696108 0.83 HSD17B10 (0.68) HPGDALOX15HSD17B10KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-58059894-A None JP disclosed
CN-116751137-B Method for preparing chloro aromatic compound by photo-induced nitroarene denitration chlorination 华中师范大学 2025-03-07 CN disclosed
CN-116751137-A Method for preparing chloro aromatic compound by photo-induced nitroarene denitration chlorination 华中师范大学 2023-09-15 CN disclosed
CN-110003271-B Process for producing aromatic compound 住友化学株式会社 2022-05-03 CN disclosed
US-11045796-B2 Process for producing aromatic compound, and palladium complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-06-29 US disclosed
CN-108368142-B Method for producing aromatic compound and palladium complex 住友化学株式会社 2021-02-19 CN disclosed
CN-106458834-B Diphenyl carbonate and method for producing same, catalyst and method for producing, recovering and reusing same, and polycarbonate 三菱化学株式会社 2019-10-25 CN disclosed
CN-110003271-A The preparation method of aromatic compound 住友化学株式会社 2019-07-12 CN disclosed
US-20180369799-A1 PROCESS FOR PRODUCING AROMATIC COMPOUND, AND PALLADIUM COMPLEX SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-12-27 US disclosed
EP-3385270-A1 METHOD FOR PRODUCING AROMATIC COMPOUND, AND PALLADIUM COMPLEX Sumitomo Chemical Company, Ltd (JP) 2018-10-10 EP disclosed
US-20010031841-A1 Procatalysts, catalyst systems, and use in olefin polymerization WESTLAKE LONGVIEW CORPORATION 2001-10-18 US disclosed
US-20010029286-A1 Procatalysts, catalyst systems, and use in OLEFIN polymerization EASTMAN CHEMICAL COMPANY, A CORP. OF DELAWARE 2001-10-11 US disclosed
US-20010025005-A1 Procatalysts, catalyst systems, and use in olefin polymerization EASTMAN CHEMICAL COMPANY, A CORPORATION OF DELAWARE 2001-09-27 US disclosed
US-6271321-B1 CATALYTIC POLYMERIZATION OR COPOLYMERIZATION OF ETHYLENE AND OLEFIN MONOMERS EASTMAN CHEMICAL COMPANY 2001-08-07 US disclosed
WO-2000075203-A1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEMICAL COMPANY (US) 2000-12-14 WO disclosed
WO-2000075202-A1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEMICAL COMPANY (US) 2000-12-14 WO disclosed
WO-2000075204-A1 PROCESS FOR PRODUCING ETHYLENE/OLEFIN INTERPOLYMERS EASTMAN CHEMICAL COMPANY (US) 2000-12-14 WO disclosed
US-4479138-A PHENYL BENZOIC ESTER TO INCREASE SENSITIVITY FUJI PHOTO FILM CO., LTD. (JP) 1984-10-23 US disclosed
JP-S5859894-A HEAT-SENSITIVE RECORDING MATERIAL FUJI PHOTO FILM CO LTD 1983-04-09 JP disclosed
US-3953410-A COORDINATION CATALYSTS SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11045796-B2 Process for producing aromatic compound, and palladium complex DDT, DRD1, DRD2 HPGD 1659/4885ALOX15 3466/4885HSD17B10 775/4885
US-20180369799-A1 PROCESS FOR PRODUCING AROMATIC COMPOUND, AND PALLADIUM COMPLEX DDT, DRD1, DRD2 HPGD 1659/4885ALOX15 3466/4885HSD17B10 775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.