SCHEMBL11331069

SCHEMBL11331069

O=C(Cl)c1ccc(-c2nc3ccccc3s2)cc1Cl

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.54
RAB9A P51151 5/20 0.52
LMNA P02545 5/20 0.52
KDM4E B2RXH2 5/20 0.52
ALDH1A1 P00352 4/20 0.52
NPC1 O15118 3/20 0.52
GAA P10253 3/20 0.52
GLA P06280 2/20 0.52
TP53 P04637 7/20 0.52
SMN1; SMN2 Q16637 4/20 0.52
HSD17B10 Q99714 2/20 0.52
PAX8 Q06710 1/20 0.52
NOD2 Q9HC29 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
POLB P06746 1/20 0.52
NFKB1 P19838 1/20 0.52
NFKB2 Q00653 1/20 0.52
RELA Q04206 1/20 0.52
HPGD P15428 3/20 0.51
CYP1A2 P05177 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11325434 0.80 MAPT (0.64) MAPTRAB9ALMNAKDM4EALDH1A1
SCHEMBL11339575 0.79 KDM4E (0.64) MAPTRAB9ALMNAKDM4EALDH1A1
SCHEMBL11757948 0.78 RAB9A (0.62) MAPTRAB9ALMNAKDM4EALDH1A1
SCHEMBL6284593 0.77 APP (0.69) MAPTRAB9ALMNAKDM4EALDH1A1
SCHEMBL11326988 0.77 RAB9A (0.61) MAPTRAB9ALMNAKDM4EALDH1A1
SCHEMBL15176829 0.76 DHODH (0.68) MAPTRAB9AKDM4EALDH1A1NPC1
SCHEMBL3374000 0.76 TP53 (0.60) MAPTRAB9ALMNAKDM4EALDH1A1
SCHEMBL29540179 0.76 APP (0.59) MAPTRAB9ALMNAKDM4EALDH1A1
SCHEMBL28608914 0.76 APP (0.59) MAPTRAB9ALMNAKDM4EALDH1A1
SCHEMBL11372271 0.76 MAPT (0.63) MAPTRAB9ALMNAKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4308194-A Heterocyclic benzoate ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1981-12-29 US disclosed
US-4075220-A FOR POLYMERS EASTMAN KODAK COMPANY (US) 1978-02-21 US disclosed
US-4065427-A Polychromophoric heterocyclic ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1977-12-27 US disclosed
US-4000148-A POLYMERS EASTMAN KODAK COMPANY (US) 1976-12-28 US disclosed
US-3957813-A BENZOXAZOLYL PHENYL AROMATIC ESTER COMPOUNDS AND THEIR USE AS ULTRAVIOLET STABILIZERS IN ORGANIC COMPOSITIONS EASTMAN KODAK COMPANY (US) 1976-05-18 US disclosed