Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | POLB | P06746 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275956 | 0.78 | TSHR (0.42) | TSHRALDH1A1MAPTPOLBTDP1 | |
| SCHEMBL3505825 | 0.75 | — | — | |
| SCHEMBL29954227 | 0.72 | TSHR (0.49) | TSHRALDH1A1MAPTPOLBTDP1 | |
| SCHEMBL1000643 | 0.71 | ALDH1A1 (0.57) | TSHRALDH1A1MAPTPOLBTDP1 | |
| SCHEMBL766361 | 0.71 | — | — | |
| SCHEMBL891217 | 0.71 | TSHR (0.46) | TSHRALDH1A1MAPTPOLBTDP1 | |
| SCHEMBL140950 | 0.71 | TSHR (0.59) | TSHRALDH1A1MAPTPOLBTDP1 | |
| SCHEMBL11342787 | 0.69 | ALDH1A1 (0.46) | TSHRALDH1A1MAPTPOLBTDP1 | |
| SCHEMBL11337543 | 0.69 | ALDH1A1 (0.46) | TSHRALDH1A1MAPTPOLBTDP1 | |
| SCHEMBL11337541 | 0.69 | ALDH1A1 (0.46) | TSHRALDH1A1MAPTPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4303689-A | Flavoring with pyrazine derivatives | FIRMENICH SA (CH) | 1981-12-01 | — | — | US | disclosed |