SCHEMBL11332122

SCHEMBL11332122

O=C1C(=Cc2cccc([N+](=O)[O-])c2)SC(=Nc2ccccc2)N1c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 9/20 0.59
▸ MEN1 O00255 8/20 0.59
▸ ALDH1A1 P00352 5/20 0.59
▸ NPSR1 Q6W5P4 1/20 0.59
▸ FAAH O00519 2/20 0.57
▸ NR1H4 Q96RI1 1/20 0.57
▸ CYP1A2 P05177 1/20 0.53
▸ POLB P06746 1/20 0.53
▸ CYP2C9 P11712 1/20 0.53
▸ CYP2C19 P33261 1/20 0.53
▸ L3MBTL1 Q9Y468 1/20 0.53
▸ MAPT P10636 3/20 0.52
▸ MAPK1 P28482 1/20 0.52
▸ GFER P55789 1/20 0.52
▸ AKR1B1 P15121 1/20 0.52
▸ LMNA P02545 2/20 0.52
▸ S1PR1 P21453 3/20 0.51
▸ S1PR3 Q99500 3/20 0.51
▸ CA2 P00918 1/20 0.50
▸ CA9 Q16790 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31310398 0.91 MGAM (0.58) KMT2AMEN1ALDH1A1NPSR1FAAH
SCHEMBL12013235 0.84 MEN1 (0.79) KMT2AMEN1ALDH1A1NPSR1FAAH
SCHEMBL11331663 0.84 MEN1 (0.79) KMT2AMEN1ALDH1A1NPSR1FAAH
SCHEMBL17309290 0.84 MEN1 (0.79) KMT2AMEN1ALDH1A1NPSR1FAAH
SCHEMBL11331666 0.84 MEN1 (0.79) KMT2AMEN1ALDH1A1NPSR1FAAH
SCHEMBL9120921 0.82 DUSP22 (0.64) KMT2AMEN1ALDH1A1NR1H4GFER
SCHEMBL17302239 0.80 MEN1 (0.60) KMT2AMEN1ALDH1A1NPSR1FAAH
SCHEMBL31310299 0.79 CA2 (0.61) KMT2AMEN1ALDH1A1NPSR1FAAH
SCHEMBL29726497 0.77 FAAH (0.63) KMT2AMEN1ALDH1A1NPSR1FAAH
SCHEMBL17302144 0.77 FAAH (0.63) KMT2AMEN1ALDH1A1NPSR1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4304769-A PESTICIDES EASTMAN KODAK COMPANY (US) 1981-12-08 — — US disclosed
US-4247627-A Photographic elements having hydrophilic colloid layers containing hydrophobic ultraviolet absorbers uniformly loaded in latex polymer particles EASTMAN KODAK COMPANY (US) 1981-01-27 — — US disclosed
US-4214047-A Photographic elements having hydrophilic colloid layers containing hydrophobic addenda uniformly loaded in latex polymer particles EASTMAN KODAK COMPANY (US) 1980-07-22 — — US disclosed
US-4203716-A Photographic elements having hydrophilic colloid layers containing hydrophobic addenda uniformly loaded in latex polymer particles EASTMAN KODAK COMPANY (US) 1980-05-20 — — US disclosed
US-4199363-A Processes for achieving uniform, efficient distribution of hydrophobic materials through hydrophilic colloid layers and loaded latex compositions EASTMAN KODAK COMPANY (US) 1980-04-22 — — US disclosed
Send feedback