SCHEMBL1133259

SCHEMBL1133259

CCCC/N=C/c1ccc(N(C)C)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.51
KDM4E B2RXH2 6/20 0.51
MAPT P10636 5/20 0.51
SMN1; SMN2 Q16637 3/20 0.51
GAA P10253 3/20 0.51
HPGD P15428 2/20 0.51
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
KMT2A Q03164 3/20 0.50
L3MBTL1 Q9Y468 3/20 0.50
MEN1 O00255 2/20 0.50
NPSR1 Q6W5P4 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA9 Q16790 1/20 0.50
TP53 P04637 1/20 0.50
THRB P10828 1/20 0.50
ALOX15 P16050 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL465253 1.00 ALDH1A1 (0.51) ALDH1A1KDM4EMAPTSMN1; SMN2GAA
SCHEMBL19821404 0.93 ALDH1A1 (0.52) ALDH1A1KDM4EMAPTSMN1; SMN2GAA
SCHEMBL19810568 0.93 ALDH1A1 (0.52) ALDH1A1KDM4EMAPTSMN1; SMN2GAA
SCHEMBL19810569 0.93 ALDH1A1 (0.52) ALDH1A1KDM4EMAPTSMN1; SMN2GAA
SCHEMBL12391383 0.93 ALDH1A1 (0.52) ALDH1A1KDM4EMAPTSMN1; SMN2GAA
SCHEMBL15367607 0.89 ALDH1A1 (0.61) ALDH1A1KDM4EMAPTSMN1; SMN2GAA
SCHEMBL4901443 0.87 ALDH1A1 (0.59) ALDH1A1KDM4EMAPTSMN1; SMN2KMT2A
SCHEMBL4901434 0.87 ALDH1A1 (0.59) ALDH1A1KDM4EMAPTSMN1; SMN2KMT2A
SCHEMBL5680683 0.87 ALDH1A1 (0.61) ALDH1A1KDM4EMAPTSMN1; SMN2GAA
SCHEMBL5680680 0.87 ALDH1A1 (0.61) ALDH1A1KDM4EMAPTSMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12415907-B2 Rubber composition and run-flat tire BRIDGESTONE CORPORATION (JP) 2025-09-16 US disclosed
US-20220363093-A1 RUN-FLAT TIRE BRIDGESTONE CORPORATION (JP) 2022-11-17 US disclosed
US-20220348746-A1 RUBBER COMPOSITION AND RUN-FLAT TIRE BRIDGESTONE CORPORATION (JP) 2022-11-03 US disclosed
EP-4039503-A1 RUBBER COMPOSITION AND RUN-FLAT TIRE BRIDGESTONE CORPORATION (JP) 2022-08-10 EP disclosed
EP-4039502-A1 RUN-FLAT TIRE BRIDGESTONE CORPORATION (JP) 2022-08-10 EP disclosed
EP-2289710-B1 Pneumatic tire BRIDGESTONE CORP (JP) 2018-11-07 EP disclosed
EP-1297974-B1 PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2017-03-15 EP disclosed
US-20110196063-A1 RUBBER COMPOSITION FOR TREAD AND TIRE USING THE RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2011-08-11 US disclosed
EP-2289710-A2 Pneumatic tire Bridgestone Corporation (JP) 2011-03-02 EP disclosed
EP-2289710-A2 Pneumatic tire Bridgestone Corporation (JP) 2011-03-02 EP disclosed
EP-2287015-A2 Pneumatic tire Bridgestone Corporation (JP) 2011-02-23 EP disclosed
EP-2287015-A2 Pneumatic tire Bridgestone Corporation (JP) 2011-02-23 EP disclosed
US-20060272760-A1 Pneumatic tire BRIDGESTONE CORPORATION 2006-12-07 US disclosed
EP-1297974-A1 PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2003-04-02 EP disclosed
US-20030015272-A1 Pneumatic tire BRIDGESTONE CORPORATION (JP) 2003-01-23 US disclosed