SCHEMBL5680683

SCHEMBL5680683

CCCCN=Cc1ccc(C=NCCCC)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.61
KMT2A Q03164 4/20 0.61
MAPT P10636 4/20 0.41
KDM4E B2RXH2 3/20 0.41
GAA P10253 1/20 0.41
TAAR1 Q96RJ0 1/20 0.40
CA2 P00918 7/20 0.40
GRIN2D O15399 1/20 0.40
GRIN3B O60391 1/20 0.40
GRIN1 Q05586 1/20 0.40
GRIN2A Q12879 1/20 0.40
GRIN2B Q13224 1/20 0.40
GRIN2C Q14957 1/20 0.40
GRIN3A Q8TCU5 1/20 0.40
MIF P14174 1/20 0.39
CA9 Q16790 4/20 0.38
MEN1 O00255 3/20 0.38
CA1 P00915 2/20 0.38
MAPK1 P28482 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5680680 1.00 ALDH1A1 (0.61) ALDH1A1KMT2AMAPTKDM4EGAA
SCHEMBL20417359 0.96 ALDH1A1 (0.57) ALDH1A1KMT2AMAPTKDM4EGAA
SCHEMBL20824903 0.96 ALDH1A1 (0.68) ALDH1A1KMT2AMAPTKDM4EGAA
SCHEMBL14196484 0.92 KMT2A (0.53) ALDH1A1KMT2AMAPTKDM4EGAA
SCHEMBL21975288 0.92 ALDH1A1 (0.53) ALDH1A1KMT2AMAPTKDM4EGAA
SCHEMBL9810599 0.91 ALDH1A1 (0.57) ALDH1A1KMT2AMAPTKDM4ETAAR1
SCHEMBL9810590 0.91 ALDH1A1 (0.57) ALDH1A1KMT2AMAPTKDM4ETAAR1
SCHEMBL5728586 0.90 KMT2A (0.52) ALDH1A1KMT2AHPGD
SCHEMBL5728585 0.90 KMT2A (0.52) ALDH1A1KMT2AHPGD
SCHEMBL474264 0.90 ALDH1A1 (0.79) ALDH1A1KMT2AMAPTKDM4ETAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1451198-B1 PROCESS FOR THE PREPARATION OF SECONDARY AND TERTIARY AMINO-FUNCTIONAL SILANES,IMINOORGANOSILANES AND/OR IMIDOORGANOSILANES GEN ELECTRIC (US) 2006-03-01 EP disclosed
US-6998499-B2 Process for the preparation of secondary and tertiary amino-functional silanes, iminoorganosilanes and/or imidoorganosilanes GENERAL ELECTRIC COMPANY (US) 2006-02-14 US disclosed
EP-1451198-A1 PROCESS FOR THE PREPARATION OF SECONDARY AND TERTIARY AMINO-FUNCTIONAL SILANES,IMINOORGANOSILANES AND/OR IMIDOORGANOSILANES GENERAL ELECTRIC COMPANY (US) 2004-09-01 EP disclosed
US-20030220513-A1 Process for the preparation of secondary and tertiary amino-functional silanes, iminoorganosilanes and/or imidoorganosilanes CROMPTON CORPORATION, A CORPORATION OF THE STATE OF DELAWARE 2003-11-27 US disclosed
US-6586612-B2 Reacting N-benzylidene aniline with 3-aminopropyltrimethoxy-silane to from N-benzylidene aminopropyltrimethoxysilane used as adhesion promoters in adhesives and sealants or couplers for plastics and glass fibers CROMPTON CORPORATION 2003-07-01 US disclosed
WO-2003044026-A1 PROCESS FOR THE PREPARATION OF SECONDARY AND TERTIARY AMINO-FUNCTIONAL SILANES, IMINOORGANOSILANES AND/OR IMIDOORGANOSILANES GENERAL ELECTRIC COMPANY (US) 2003-05-30 WO disclosed
US-20030097014-A1 PROCESS FOR THE PREPARATION OF SECONDARY AND TERTIARY AMINO-FUNCTIONAL SILANES, IMINOORGANOSILANES AND/OR IMIDOORGANOSILANES MOMENTIVE PERFORMANCE MATERIALS INC. 2003-05-22 US disclosed
US-4082768-A NEW IMIDES OF UNSATURATED DICARBOXYLIC ACIDS, PROCESSES FOR THEIR MANUFACTURE, AND THEIR USE CIBA-GEIGY CORPORATION (US) 1978-04-04 US disclosed
US-3960812-A DIELECTRICS, MECHANICAL PROPERTIES CIBA-GEIGY CORPORATION (US) 1976-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030097014-A1 PROCESS FOR THE PREPARATION OF SECONDARY AND TERTIARY AMINO-FUNCTIONAL SILANES, IMINOORGANOSILANES AND/OR IMIDOORGANOSILANES INMT, SI, DAO ALDH1A1 805/4885KMT2A 748/4885MAPT 4172/4885
US-20030220513-A1 Process for the preparation of secondary and tertiary amino-functional silanes, iminoorganosilanes and/or imidoorganosilanes INMT, SI, DAO ALDH1A1 805/4885KMT2A 748/4885MAPT 4172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.