SCHEMBL1133339

SCHEMBL1133339

CCCC(Cl)CC[Si](OC)(OC)OC

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7765572 0.87 LMNA (0.40) LMNA
SCHEMBL1132674 0.85 LMNA (0.43) LMNA
SCHEMBL29145273 0.84 LMNA (0.31) LMNA
SCHEMBL1132638 0.80
SCHEMBL11370848 0.79
SCHEMBL9245791 0.79 TP53 (0.31)
SCHEMBL28789852 0.78
SCHEMBL14213178 0.76 LMNA (0.36) LMNA
SCHEMBL7764310 0.75 LMNA (0.30) LMNA
SCHEMBL1133060 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2287212-B1 A catalyst component for ethylene polymerization, preparation thereof and a catalyst comprising the catalyst component CHINA PETROLEUM & CHEMICAL (CN) 2014-03-26 EP claimed
US-8268945-B2 Catalyst component for ethylene polymerization, preparation thereof, and a catalyst comprising the catalyst component CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2012-09-18 US claimed
US-20110046325-A1 CATALYST COMPONENT FOR ETHYLENE POLYMERIZATION, PREPARATION THEREOF, AND A CATALYST COMPRISING THE CATALYST COMPONENT CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2011-02-24 US claimed
EP-2287212-A1 A catalyst component for ethylene polymerization, preparation thereof and a catalyst comprising the catalyst component China Petroleum & Chemical Corporation (CN) 2011-02-23 EP claimed
EP-2287212-B1 A catalyst component for ethylene polymerization, preparation thereof and a catalyst comprising the catalyst component CHINA PETROLEUM & CHEMICAL (CN) 2014-03-26 EP disclosed
US-8268945-B2 Catalyst component for ethylene polymerization, preparation thereof, and a catalyst comprising the catalyst component CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2012-09-18 US disclosed
US-20110046325-A1 CATALYST COMPONENT FOR ETHYLENE POLYMERIZATION, PREPARATION THEREOF, AND A CATALYST COMPRISING THE CATALYST COMPONENT CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2011-02-24 US disclosed
EP-2287212-A1 A catalyst component for ethylene polymerization, preparation thereof and a catalyst comprising the catalyst component China Petroleum & Chemical Corporation (CN) 2011-02-23 EP disclosed