SCHEMBL7765572

SCHEMBL7765572

CCCCC(Cl)CC[Si](OC)(OC)OC

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.40
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
DNM1 Q05193 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1132674 0.94 LMNA (0.43) LMNA
SCHEMBL1133339 0.87 LMNA (0.34) LMNA
SCHEMBL29145273 0.80 LMNA (0.31) LMNA
SCHEMBL28280627 0.77 LMNA (0.41) LMNACA1CA2DNM1
SCHEMBL4540450 0.76 DNM1 (0.45) LMNACA1CA2DNM1
SCHEMBL1132920 0.76 OPRM1 (0.35)
SCHEMBL9245791 0.76 TP53 (0.31)
SCHEMBL18983159 0.75 MMP13 (0.41) LMNACA1CA2DNM1
SCHEMBL12804736 0.75 LMNA (0.40) LMNACA1CA2
SCHEMBL27312894 0.75 ALDH1A1 (0.45) LMNACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0709392-B1 Process for the preparation of 3-halogeno- or -pseudohalogeno-alkylsilane esters, respectively DEGUSSA (DE) 2001-05-16 EP disclosed
US-5616762-A Process for the preparation of 3-halo-and pseudohalo-alkylsilane esters HUELS AKTIENGESELLSCHAFT (DE) 1997-04-01 US disclosed
EP-0709392-A1 Process for the preparation of 3-halogeno- or -pseudohalogeno-alkylsilane esters, respectively HÜLS AKTIENGESELLSCHAFT (DE) 1996-05-01 EP disclosed