Phthalic Acid

Phthalic Acid

SCHEMBL11333396

C=CCNCC=C.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.56

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.56
ALOX15 P16050 1/20 0.56
KMT2A Q03164 2/20 0.51
HPGD P15428 3/20 0.50
CYP1A2 P05177 1/20 0.50
KDM4E B2RXH2 3/20 0.47
MAPT P10636 2/20 0.47
LMNA P02545 1/20 0.46
APEX1 P27695 1/20 0.46
AKR1C3 P42330 1/20 0.45
CYP3A4 P08684 1/20 0.44
CA1 P00915 2/20 0.43
CA9 Q16790 2/20 0.43
CA12 O43570 1/20 0.43
CA2 P00918 1/20 0.43
HMGB1 P09429 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
CA7 P43166 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4421495 0.87 ALDH1A1 (0.50) ALDH1A1ALOX15KMT2AHPGDCYP1A2
Benzoic Acid SCHEMBL983379 0.84 TSHR (0.56) ALDH1A1ALOX15KMT2AHPGDKDM4E
Pyromellitic Acid SCHEMBL31186776 0.83 KDM4E (0.39) ALDH1A1ALOX15KMT2AHPGDCYP1A2
SCHEMBL5885064 0.83 HPGD (0.68) ALDH1A1ALOX15KMT2AHPGDCYP1A2
SCHEMBL11567426 0.81 MAPT (0.54) ALDH1A1KMT2AHPGDCYP1A2KDM4E
SCHEMBL28782315 0.81 ALDH1A1 (0.49) ALDH1A1KMT2AHPGDKDM4EMAPT
Phthalic Acid SCHEMBL23929048 0.81 ALDH1A1 (0.64) ALDH1A1ALOX15KMT2AHPGDKDM4E
Phthalic Acid SCHEMBL21332399 0.81 ALDH1A1 (0.64) ALDH1A1ALOX15KMT2AHPGDKDM4E
Benzophenone SCHEMBL7590791 0.80 ALDH1A1 (0.69) ALDH1A1ALOX15KMT2AHPGDCYP1A2
SCHEMBL587283 0.79 ALDH1A1 (0.57) ALDH1A1ALOX15KMT2AHPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4306073-A ADHESION PROMOTERS FOR GLASS FIBERS CIBA-GEIGY CORPORATION (US) 1981-12-15 US disclosed
US-4261898-A ADHESION PROMOTERS, CURING AGENTS CIBA-GEIGY CORPORATION (US) 1981-04-14 US disclosed
US-4200724-A ADHESION PROMOTERS BETWEEN INORGANIC SOLIDS AND ORGANIC RESINS CIBA-GEIGY CORPORATION (US) 1980-04-29 US disclosed
US-4176124-A ADHESION PROMOTERS BETWEEN SOLIDS AND ORGANIC RESINS OR CURING AGENTS FOR EPOXIDE RESINS CIBA-GEIGY CORPORATION (US) 1979-11-27 US disclosed
US-4158662-A STORAGE STABLE MOLDING MATERIAL CIBA-GEIGY CORPORATION (US) 1979-06-19 US disclosed
US-4140703-A CURING AGENTS FOR POLYEPOXIDES CIBA-GEIGY CORPORATION (US) 1979-02-20 US disclosed
US-4127712-A Phthalic acid diesters or ester-amides substituted by alkenylamino groups CIBA-GEIGY CORPORATION (US) 1978-11-28 US disclosed