Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | DAO | P14920 | 1/20 | 0.56 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzophenone SCHEMBL7590791 | 0.88 | ALDH1A1 (0.69) | KDM4EALDH1A1HPGDLMNAPOLB | |
| Acetophenone SCHEMBL7587242 | 0.85 | KDM4E (0.53) | KDM4EALDH1A1HPGDLMNAPOLB | |
| Benzoyl Chloride SCHEMBL21084684 | 0.85 | KDM4E (0.53) | KDM4EALDH1A1HPGDLMNAPOLB | |
| Phthalic Acid SCHEMBL11333396 | 0.84 | ALDH1A1 (0.56) | NAPRTKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL2521368 | 0.82 | KDM4E (0.49) | KDM4EALDH1A1HPGDLMNAPOLB | |
| Benzoic Acid SCHEMBL3266320 | 0.81 | TSHR (0.64) | TSHRDAONAPRTKDM4EALDH1A1 | |
| SCHEMBL4413289 | 0.81 | KDM4E (0.60) | KDM4EALDH1A1HPGDLMNAPOLB | |
| Benzoic Acid SCHEMBL971091 | 0.79 | TSHR (0.61) | TSHRDAONAPRTKDM4EALDH1A1 | |
| Benzoic Acid SCHEMBL9740671 | 0.79 | TSHR (0.61) | TSHRDAONAPRTKDM4EALDH1A1 | |
| Benzoic Acid SCHEMBL9472196 | 0.79 | TSHR (0.61) | TSHRDAONAPRTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2270110-B1 | PIGMENT-DISPERSED COMPOSITION, COLORED PHOTOSENSITIVE COMPOSITION, PHOTOCURABLE COMPOSITION, COLOR FILTER, LIQUID CRYSTAL DISPLAY ELEMENT, AND SOLID IMAGE PICKUP ELEMENT | FUJIFILM CORP (JP) | 2015-02-25 | — | — | EP | disclosed |
| US-8362140-B2 | Pigment-dispersed composition, colored photosensitive composition, photocurable composition, color filter, liquid crystal display device, and solid-state image pickup device | FUJIFILM CORPORATION (JP) | 2013-01-29 | — | — | US | disclosed |
| US-20110014401-A1 | PIGMENT-DISPERSED COMPOSITION, COLORED PHOTOSENSITIVE COMPOSITION, PHOTOCURABLE COMPOSITION, COLOR FILTER, LIQUID CRYSTAL DISPLAY DEVICE, AND SOLID-STATE IMAGE PICKUP DEVICE | FUJIFILM CORPORATION (JP) | 2011-01-20 | — | — | US | disclosed |
| EP-2270110-A1 | PIGMENT-DISPERSED COMPOSITION, COLORED PHOTOSENSITIVE COMPOSITION, PHOTOCURABLE COMPOSITION, COLOR FILTER, LIQUID CRYSTAL DISPLAY ELEMENT, AND SOLID IMAGE PICKUP ELEMENT | FUJIFILM Corporation (JP) | 2011-01-05 | — | — | EP | disclosed |
| US-6071983-A | FOR TREATING TOOTH SURFACE BY FACILE HANDLING; FOR RESTORING A TOOTH-SURFACE WITH COATING MATERIAL OR RESTORING DENTAL RESTORATIVE RESINS | SUN MEDICAL CO., LTD. (JP) | 2000-06-06 | — | — | US | disclosed |
| US-5834532-A | BLEND OF POLYMERIZABLE MONOMER HAVING ACIDIC GROUPS AND AN INITIATOR | SUN MEDICAL CO., LTD. (JP) | 1998-11-10 | — | — | US | disclosed |
| US-5730900-A | Film and process for preparation of the same and liquid crystal display | FUJI PHOTO FILM CO., LTD. (JP) | 1998-03-24 | — | — | US | disclosed |
| US-5635105-A | ANISOTROPIC LAYER HAS NEGATIVE BIREFRINGENCE AND COMPRISES POLYMER HAVING DISCOTIC STRUCTURE | FUJI PHOTO FILM CO., LTD. (JP) | 1997-06-03 | — | — | US | disclosed |
| US-5587406-A | APPLYING CURABLE PRIMER COMPOSITION COMPRISING POLYMERIZABLE MONOMER HAVING ACID GROUP AND POLYMERIZABLE MONOMER HAVING HYDROXYL GROUP AND POLYMERIZATION INITIATOR TO TOOTH | SUN MEDICAL CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| US-5530038-A | CONTAINING UNSATURATED MONOMER WITH ACIDIC GROUP, UNSATURATED MONOMER WITH HYDROXYL GROUP, POLYMERIZATION INITIATOR, AMINE COMPOUND, ZIRCONIUM OXIDE AND ORGANIC COMPOSITE FILLERS | SUN MEDICAL CO., LTD. (JP) | 1996-06-25 | — | — | US | disclosed |
| US-4562278-A | SUNSCREEN AGENTS | DOW CORNING, LTD. (GB) | 1985-12-31 | — | — | US | disclosed |
| EP-0138590-A2 | Organosilicon compounds and preparation and use thereof | Dow Corning Limited (GB) | 1985-04-24 | — | — | EP | disclosed |
| US-4501767-A | Multicoat forming method | NIPPON PAINT CO., LTD. (JP) | 1985-02-26 | — | — | US | disclosed |