SCHEMBL11333427

SCHEMBL11333427

CCCCCCCCCCCCCCCCN1C(=O)/C(=C/c2ccccc2)S/C1=N/c1ccccc1

nearest known ligand 0.72

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.72
▸ HPGD P15428 1/20 0.72
▸ SMN1; SMN2 Q16637 1/20 0.72
▸ FAAH O00519 1/20 0.69
▸ CA9 Q16790 10/20 0.59
▸ MGAM O43451 2/20 0.59
▸ CA12 O43570 2/20 0.59
▸ CA1 P00915 2/20 0.59
▸ CA2 P00918 2/20 0.59
▸ AURKA O14965 1/20 0.55
▸ TDP1 Q9NUW8 1/20 0.55
▸ PSMB8 P28062 1/20 0.52
▸ PTPN1 P18031 1/20 0.51
▸ ACP1 P24666 1/20 0.51
▸ S1PR1 P21453 1/20 0.51
▸ S1PR3 Q99500 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11333429 1.00 LMNA (0.72) LMNAHPGDSMN1; SMN2FAAHCA9
SCHEMBL17295616 0.95 LMNA (0.75) LMNAHPGDSMN1; SMN2FAAHCA9
SCHEMBL17295612 0.95 LMNA (0.75) LMNAHPGDSMN1; SMN2FAAHCA9
SCHEMBL17295562 0.92 LMNA (0.62) LMNAHPGDSMN1; SMN2FAAHCA9
SCHEMBL17295565 0.92 LMNA (0.62) LMNAHPGDSMN1; SMN2FAAHCA9
SCHEMBL17302244 0.86 FAAH (0.66) LMNAHPGDSMN1; SMN2FAAHCA9
SCHEMBL17302233 0.86 CA9 (0.68) LMNAHPGDSMN1; SMN2FAAHCA9
SCHEMBL11329893 0.85 CA9 (0.77) LMNAHPGDSMN1; SMN2FAAHCA9
SCHEMBL11329898 0.85 CA9 (0.77) LMNAHPGDSMN1; SMN2FAAHCA9
SCHEMBL10667429 0.85 LMNA (0.55) LMNAHPGDSMN1; SMN2FAAHPSMB8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4304769-A PESTICIDES EASTMAN KODAK COMPANY (US) 1981-12-08 — — US disclosed
US-4247627-A Photographic elements having hydrophilic colloid layers containing hydrophobic ultraviolet absorbers uniformly loaded in latex polymer particles EASTMAN KODAK COMPANY (US) 1981-01-27 — — US disclosed
US-4214047-A Photographic elements having hydrophilic colloid layers containing hydrophobic addenda uniformly loaded in latex polymer particles EASTMAN KODAK COMPANY (US) 1980-07-22 — — US disclosed
US-4203716-A Photographic elements having hydrophilic colloid layers containing hydrophobic addenda uniformly loaded in latex polymer particles EASTMAN KODAK COMPANY (US) 1980-05-20 — — US disclosed
US-4199363-A Processes for achieving uniform, efficient distribution of hydrophobic materials through hydrophilic colloid layers and loaded latex compositions EASTMAN KODAK COMPANY (US) 1980-04-22 — — US disclosed
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