Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 13/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11198946 | 0.84 | ACE (0.47) | ACEMMEACE2PPARGPPARA | |
| SCHEMBL4576379 | 0.82 | PPARG (0.35) | ACEMMEACE2PPARGPPARA | |
| SCHEMBL4576383 | 0.82 | PPARG (0.35) | ACEMMEACE2PPARGPPARA | |
| SCHEMBL11333699 | 0.78 | PPARG (0.33) | ACEMMEACE2PPARGPPARA | |
| SCHEMBL11337780 | 0.77 | ACE (0.35) | ACEMMEACE2 | |
| SCHEMBL8582126 | 0.76 | MAPT (0.48) | ACEPPARGPPARA | |
| SCHEMBL18954453 | 0.71 | PPARA (0.55) | ACEPPARGPPARA | |
| SCHEMBL20122455 | 0.70 | ACE (0.48) | ACEMMEACE2 | |
| SCHEMBL11331818 | 0.69 | ACE (0.43) | ACEMMEACE2PPARGPPARA | |
| SCHEMBL20122457 | 0.68 | ACE (0.46) | ACEMMEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4255446-A | SUPPRESSING LIVER DISORDERS | SANTEN PHARMACEUTICAL CO. LTD. (JP) | 1981-03-10 | — | — | US | claimed |
| US-4255446-A | SUPPRESSING LIVER DISORDERS | SANTEN PHARMACEUTICAL CO. LTD. (JP) | 1981-03-10 | — | — | US | disclosed |