Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.35 |
| ▸ | MME | P08473 | 2/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20122455 | 0.84 | ACE (0.48) | ACEMMEACE2KDM4EMAPT | |
| SCHEMBL11333708 | 0.77 | ACE (0.34) | ACEMMEACE2 | |
| SCHEMBL11337774 | 0.77 | CPB2 (0.36) | ACEMMEACE2KDM4EMAPT | |
| SCHEMBL27191518 | 0.75 | CPB2 (0.37) | ACEMMEKDM4EMAPTTHRB | |
| SCHEMBL27205923 | 0.75 | CPB2 (0.37) | ACEMMEKDM4EMAPTTHRB | |
| Dacisteine SCHEMBL1814125 | 0.73 | MAPT (0.55) | ACEMMEKDM4EMAPTTHRB | |
| Dacisteine SCHEMBL2402188 | 0.73 | MAPT (0.55) | ACEMMEKDM4EMAPTTHRB | |
| SCHEMBL31234465 | 0.73 | CPB2 (0.36) | ACEMMEKDM4EMAPTTHRB | |
| SCHEMBL11331818 | 0.71 | ACE (0.43) | ACEMMEACE2MAPTALDH1A1 | |
| SCHEMBL11198946 | 0.71 | ACE (0.47) | ACEMMEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4255446-A | SUPPRESSING LIVER DISORDERS | SANTEN PHARMACEUTICAL CO. LTD. (JP) | 1981-03-10 | — | — | US | claimed |
| US-4255446-A | SUPPRESSING LIVER DISORDERS | SANTEN PHARMACEUTICAL CO. LTD. (JP) | 1981-03-10 | — | — | US | disclosed |