SCHEMBL1133409

SCHEMBL1133409

CO[Si](CCCN(C=O)CCNC=O)(OC)OC.[SiH4]

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 3/20 0.32
ADH1A P07327 3/20 0.32
ADH7 P40394 3/20 0.32
ADH1C P00326 2/20 0.32
EPHX1 P07099 1/20 0.32
ADH4 P08319 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1133010 0.98 ADH1B (0.33) ADH1BADH1AADH7ADH1CEPHX1
SCHEMBL1132905 0.83 ADH1B (0.35) ADH1BADH1AADH7ADH1CEPHX1
SCHEMBL555422 0.77 ADH1B (0.48) ADH1BADH1AADH7ADH1CEPHX1
SCHEMBL28061134 0.75 ADH1B (0.43) ADH1BADH1AADH7ADH1CEPHX1
SCHEMBL1132677 0.73 ADH1B (0.39) ADH1BADH1AADH7ADH1CEPHX1
SCHEMBL23685944 0.69 ADH1B (0.46) ADH1BADH1AADH7ADH1CEPHX1
SCHEMBL21654410 0.69 ADH1B (0.46) ADH1BADH1AADH7ADH1CEPHX1
SCHEMBL18596478 0.68 LMNA (0.30)
SCHEMBL22426540 0.68 ADH1B (0.37) ADH1BADH1AADH7ADH1CEPHX1
Hydrochloric Acid SCHEMBL9336075 0.67 LMNA (0.51) ADH1BADH1AADH7ADH1CEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1853675-B1 A BINDER COMPOSITION SIGMA COATINGS BV (NL) 2011-07-27 EP disclosed
US-20110098397-A1 Binder Composition PPG B.V. (NL) 2011-04-28 US disclosed
EP-2287261-A2 Method of Preparing an Aqueous Oligomeric or Polymeric Compound SIGMA COATINGS B.V. (NL) 2011-02-23 EP disclosed