SCHEMBL1133422

SCHEMBL1133422

O=C(O)CCCc1c(N2C(=O)CCC2=O)cc2ccc3cccc4ccc1c2c34

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.54
MEN1 O00255 3/20 0.54
CYP1A2 P05177 3/20 0.42
KDM4E B2RXH2 3/20 0.42
CYP2D6 P10635 2/20 0.42
ALDH1A1 P00352 1/20 0.42
GLA P06280 1/20 0.42
POLB P06746 1/20 0.42
HPGD P15428 1/20 0.42
HSD17B10 Q99714 1/20 0.42
CYP2C19 P33261 1/20 0.39
S1PR5 Q9H228 1/20 0.36
FAAH O00519 1/20 0.34
SLC22A12 Q96S37 1/20 0.34
EGFR P00533 2/20 0.33
GAA P10253 1/20 0.33
HTR1A P08908 1/20 0.33
HTR1D P28221 1/20 0.33
HTR1B P28222 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrene SCHEMBL29695823 0.96 KMT2A (0.50) KMT2AMEN1CYP1A2KDM4ECYP2D6
SCHEMBL8602070 0.78 KMT2A (0.74) KMT2AMEN1CYP1A2KDM4ECYP2D6
SCHEMBL9740053 0.77 KMT2A (0.54) KMT2AMEN1CYP1A2KDM4ECYP2D6
Butyric Acid SCHEMBL1284593 0.77 KMT2A (0.47) KMT2AMEN1CYP1A2KDM4ECYP2D6
SCHEMBL5352777 0.76 KMT2A (0.75) KMT2AMEN1CYP1A2KDM4ECYP2D6
Pyrene SCHEMBL5535684 0.75 KMT2A (0.38) KMT2AMEN1CYP1A2KDM4ECYP2D6
Pyrene SCHEMBL1061899 0.75 KMT2A (0.38) KMT2AMEN1CYP1A2KDM4ECYP2D6
SCHEMBL29618995 0.73 KMT2A (0.58) KMT2AMEN1CYP1A2KDM4ECYP2D6
SCHEMBL8387710 0.72 KMT2A (0.71) KMT2AMEN1CYP1A2KDM4ECYP2D6
SCHEMBL5349813 0.72 AKR1C3 (0.35) KMT2AMEN1CYP1A2KDM4ECYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1412518-B1 SORTING AND IMMOBILIZATION SYSTEM FOR NUCLEIC ACIDS USING SYNTHETIC BINDING SYSTEMS NANOGEN RECOGNOMICS GMBH (DE) 2010-05-12 EP claimed
EP-1067134-B1 Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system NANOTRONICS INC (US) 2004-07-28 EP claimed
EP-0620822-B1 HYBRIDIZATION OF POLYNUCLEOTIDES CONJUGATED WITH CHROMOPHORES AND FLUOROPHORES TO GENERATE DONOR-TO-DONOR ENERGY TRANSFER SYSTEM NANOTRONICS INC (US) 2001-05-30 EP claimed
EP-0870063-B1 FLUORESCENCE DETECTION ASSAY FOR HOMOGENEOUS PCR HYBRIDIZATION SYSTEMS PERKIN ELMER CORP (US) 2000-07-26 EP claimed
US-6432632-B1 None US disclosed
CN-119677872-A Polynucleotide detection 生物保真有限公司 2025-03-21 CN disclosed
CN-110651051-B Compositions and methods for detecting Babesia 豪夫迈·罗氏有限公司 2023-08-25 CN disclosed
CN-108410964-B Method for reducing quantization error caused by optical artifacts in digital polymerase chain reaction 豪夫迈·罗氏有限公司 2023-08-25 CN disclosed
CN-110100012-B COBRA probe for detecting marker of epidemic ribosomal type of clostridium difficile 豪夫迈·罗氏有限公司 2023-05-16 CN disclosed
EP-3147371-B1 NOVEL METHOD FOR DETECTING DETECTION OBJECT IN SAMPLE, AND DETECTION KIT USING SAME NANOENTEK INC (KR) 2022-12-28 EP disclosed
WO-2022149449-A1 TRANSISTOR-TYPE POLYAMINE SENSOR 国立大学法人 東京大学 2022-07-14 WO disclosed
US-20200399398-A1 TUBULAR NANOSTRUCTURE TARGETED TO CELL MEMBRANE ENTERPRISE SCIENCE FUND, LLC 2020-12-24 US disclosed
EP-0957365-B1 FLUORESCENCE POLARIZATION METHOD MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 2006-02-01 EP disclosed
EP-0969279-B1 Fluorescence polarization method at multiple wavelengths MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 2003-10-29 EP disclosed
US-20020150890-A1 Fluorescence polarization method MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. 2002-10-17 US disclosed
US-6448018-B1 Fluorescence polarization method at multiple wavelengths MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2002-09-10 US disclosed
US-6432632-B2 Fluorescence polarization method MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2002-08-13 US disclosed
US-20010051331-A1 FLUORESCENCE POLARIZATION METHOD MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2001-12-13 US disclosed
EP-0969279-A2 Fluorescence polarization method at multiple wavelengths MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2000-01-05 EP disclosed
EP-0957365-A1 FLUORESCENCE POLARIZATION METHOD Matsushita Electric Industrial Co., Ltd. (JP) 1999-11-17 EP disclosed