Butyric Acid

Butyric Acid

SCHEMBL1284593

CCCC(=O)O.O=C1CCC(=O)N1c1ccc2ccc3cccc4ccc1c2c34

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.47
ALDH1A1 P00352 7/20 0.47
KDM4E B2RXH2 6/20 0.47
HPGD P15428 6/20 0.47
MEN1 O00255 3/20 0.47
HSD17B10 Q99714 3/20 0.47
CYP1A2 P05177 2/20 0.47
GLA P06280 2/20 0.47
POLB P06746 1/20 0.47
CYP2D6 P10635 1/20 0.47
MAPT P10636 4/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
HTT P42858 1/20 0.37
RECQL P46063 1/20 0.37
NPC1 O15118 1/20 0.35
MAPK1 P28482 1/20 0.34
FAAH O00519 1/20 0.34
CYP3A4 P08684 2/20 0.34
TSHR P16473 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3263559 0.85 ALDH1A1 (0.45) KMT2AALDH1A1KDM4EHPGDMEN1
Pyrene SCHEMBL29695823 0.83 KMT2A (0.50) KMT2AALDH1A1KDM4EHPGDMEN1
Pyrene SCHEMBL5502107 0.82 KMT2A (0.46) KMT2AALDH1A1KDM4EHPGDMEN1
Pyrene SCHEMBL1061899 0.81 KMT2A (0.38) KMT2AALDH1A1KDM4EHPGDMEN1
Pyrene SCHEMBL5535684 0.81 KMT2A (0.38) KMT2AALDH1A1KDM4EHPGDMEN1
SCHEMBL718047 0.79 ALDH1A1 (0.43) KMT2AALDH1A1KDM4EHPGDHSD17B10
Pyrene SCHEMBL9435802 0.78 HPGD (0.59) KMT2AALDH1A1KDM4EHPGDMEN1
Pyrene SCHEMBL30069714 0.78 HPGD (0.59) KMT2AALDH1A1KDM4EHPGDMEN1
Pyrene SCHEMBL38210 0.78 HPGD (0.59) KMT2AALDH1A1KDM4EHPGDMEN1
Aminopyrene SCHEMBL28966047 0.78 KMT2A (0.43) KMT2AALDH1A1KDM4EHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1412518-B1 SORTING AND IMMOBILIZATION SYSTEM FOR NUCLEIC ACIDS USING SYNTHETIC BINDING SYSTEMS NANOGEN RECOGNOMICS GMBH (DE) 2010-05-12 EP claimed
JP-4388369-B2 2009-12-24 JP claimed
US-20070042386-A1 Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system NANOGEN, INC. 2007-02-22 US claimed
US-6911310-B2 Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system NANOGEN, INC. (US) 2005-06-28 US claimed
US-6893822-B2 Enzymatic modification of a nucleic acid-synthetic binding unit conjugate NANOGEN RECOGNOMICS GMBH (DE) 2005-05-17 US claimed
JP-2004536317-A 2004-12-02 JP claimed
EP-1067134-B1 Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system NANOTRONICS INC (US) 2004-07-28 EP claimed
EP-1412518-A2 SORTING AND IMMOBILIZATION SYSTEM FOR NUCLEIC ACIDS USING SYNTHETIC BINDING SYSTEMS Nanogen Recognomics GmbH (DE) 2004-04-28 EP claimed
US-20030175702-A1 Sorting and immobilization system for nucleic acids using synthetic binding systems SANOFI-AVENTIS S.A. (FR) 2003-09-18 US claimed
US-20030054361-A1 Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system NANOGEN, INC. (US) 2003-03-20 US claimed
WO-2003008638-A2 SORTING AND IMMOBILIZATION SYSTEM FOR NUCLEIC ACIDS USING SYNTHETIC BIDNING SYSTEMS NANOGEN RECOGNOMICS GMBH (DE) 2003-01-30 WO claimed
EP-0620822-B1 HYBRIDIZATION OF POLYNUCLEOTIDES CONJUGATED WITH CHROMOPHORES AND FLUOROPHORES TO GENERATE DONOR-TO-DONOR ENERGY TRANSFER SYSTEM NANOTRONICS INC (US) 2001-05-30 EP claimed
EP-1067134-A2 Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system NANOTRONICS, INC. (US) 2001-01-10 EP claimed
US-6162603-A Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system NANOGEN, INC. (US) 2000-12-19 US claimed
US-5565322-A PHOTOELECTRIC DEVICES; DETECTORS; MEDICAL DIAGNOSIS NANOGEN, INC. (US) 1996-10-15 US claimed
US-5532129-A Self-organizing molecular photonic structures based on chromophore- and fluorophore-containing polynucleotides and methods of their use ENTERPRISE PARTNERS II, L.P. (US) 1996-07-02 US claimed
EP-0620822-A4 HYBRIDIZATION OF POLYNUCLEOTIDES CONJUGATED WITH CHROMOPHORES AND FLUOROPHORES TO GENERATE DONOR-TO-DONOR ENERGY TRANSFER SYSTEM. NANOTRONICS INC (US) 1996-01-10 EP claimed
EP-0620822-A1 HYBRIDIZATION OF POLYNUCLEOTIDES CONJUGATED WITH CHROMOPHORES AND FLUOROPHORES TO GENERATE DONOR-TO-DONOR ENERGY TRANSFER SYSTEM NANOTRONICS, INC. (US) 1994-10-26 EP claimed
WO-1993009128-A1 HYBRIDIZATION OF POLYNUCLEOTIDES CONJUGATED WITH CHROMOPHORES AND FLUOROPHORES TO GENERATE DONOR-TO-DONOR ENERGY TRANSFER SYSTEM NANOTRONICS, INC. (US) 1993-05-13 WO claimed
US-20240241079-A1 TRANSISTOR-TYPE POLYAMINE SENSOR THE UNIVERSITY OF TOKYO (JP) 2024-07-18 US disclosed
EP-4276455-A1 TRANSISTOR-TYPE POLYAMINE SENSOR The University of Tokyo (JP) 2023-11-15 EP disclosed
EP-2491953-B1 OPTICAL IMAGING CONTRAST AGENT, USE AND DEVICE THEREOF KYUNGPOOK NAT UNIV IND ACADEMIC COOP FOUND (KR) 2021-05-19 EP disclosed
CN-110511939-A Nucleosides, nucleotide and nucleic acid of modification and application thereof MODERNATX INC 2019-11-29 CN disclosed
CN-103974724-B Modified nucleosides, nucleotides and nucleic acids and uses thereof 现代泰克斯公司 2019-08-30 CN disclosed
CN-110168367-A Biological thiol detection combination object comprising redox regulatory protein 汉阳大学校产学协力团 2019-08-23 CN disclosed
CN-110073005-A Method for detecting norovirus 奎斯特诊断投资有限责任公司 2019-07-30 CN disclosed
CN-109804082-A Method for detecting intracranial tumors 奎斯特诊断投资有限责任公司 2019-05-24 CN disclosed
CN-109796524-A Desmoglein2 (DSG2) conjugated protein and application thereof 华盛顿大学商业化中心 2019-05-24 CN disclosed
CN-109153699-A Method for detecting Bordetella 奎斯特诊断投资有限责任公司 2019-01-04 CN disclosed
CN-109073620-A Method for preventing or reducing acute kidney injury 健康跨度DX公司 2018-12-21 CN disclosed
CN-105008535-B Desmoglein 2(DSG2) binding proteins and uses thereof 华盛顿大学商业化中心 2018-10-16 CN disclosed
CN-108410964-A A method of for reducing the quantization error caused by optical artifacts in digital polymerase chain reaction 豪夫迈·罗氏有限公司 2018-08-17 CN disclosed
CN-105849563-B Microfluidic assay devices and production and preparation method thereof 加利福尼亚大学董事会 2018-07-27 CN disclosed
CN-107532209-A Multiplex PCR for detecting gene fusion 豪夫迈·罗氏有限公司 2018-01-02 CN disclosed
US-20170371042-A1 CONTRAST AGENT FOR OPTICAL IMAGING, USE THEREOF AND APPARATUS USING THE SAME KYUNGPOOK NATIONAL UNIV INDUSTRY- ACADEMIC COOPERATION FOUNDATION (KR) 2017-12-28 US disclosed
CN-107429226-A Luterion and its separation and culture method 株式会社露太利温 2017-12-01 CN disclosed
CN-101925677-B Assay for detecting genetic abnormalities in genomic nucleic acids 奎斯特诊断投资公司 2017-08-15 CN disclosed
CN-107041146-A Desmoglein 2(DSG2) binding proteins and uses thereof 华盛顿大学商业化中心 2017-08-11 CN disclosed
CN-106817904-A T cell balanced gene expression, compositions of matter and methods of use thereof 博德研究所 2017-06-09 CN disclosed
CN-104126121-B Novel method for detecting antigen, and apparatus using same 纳诺恩科技有限公司 2017-02-22 CN disclosed
CN-106460056-A NOVEL METHOD FOR DETECTING DETECTION OBJECT IN SAMPLE, AND DETECTION KIT USING SAME 纳诺恩科技有限公司 2017-02-22 CN disclosed
CN-106170553-A Modified nucleic acid molecules and uses thereof 现代治疗公司 2016-11-30 CN disclosed
CN-106029863-A Microfluidic devices and methods of making and using the same 贝克顿·迪金森公司 2016-10-12 CN disclosed
CN-101903537-B bordetella detection assay 奎斯特诊断投资公司 2016-08-10 CN disclosed
CN-105849563-A Microfluidic assay devices and methods for making and using the same 加利福尼亚大学董事会 2016-08-10 CN disclosed
CN-105723280-A Producing separation medium using grayscale mask 加利福尼亚大学董事会 2016-06-29 CN disclosed
CN-105658069-A Immunomodulatory potential of pluripotent stromal cell (MSC) populations 贝克顿·迪金森公司 2016-06-08 CN disclosed
US-9353120-B2 Tetraaza macrocyclic compound, preparation method thereof and use thereof KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2016-05-31 US disclosed
US-20150316658-A1 CONTRAST AGENT FOR OPTICAL IMAGING, USE THEREOF AND APPARATUS USING THE SAME KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2015-11-05 US disclosed
US-20150291608-A1 NOVEL TETRAAZA MACROCYCLIC COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2015-10-15 US disclosed
US-9061078-B2 Tetraaza macrocyclic compound, preparation method thereof and use thereof KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2015-06-23 US disclosed
CN-104126121-A Novel method for detecting antigen, and apparatus using same NANOENTEK INC 2014-10-29 CN disclosed
CN-101680023-B Methods for detecting methicillin-resistant s. aureus as well as primers, probes and kits for the same MAYO FOUNDATION 2014-07-23 CN disclosed
CN-103534359-A A method of analyzing chromosomal translocations and a system therefore VENTANA MED SYST INC 2014-01-22 CN disclosed
US-8486528-B2 Temperature-sensitive nano-carriers GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2013-07-16 US disclosed
US-20130123466-A1 SIMULTANEOUS SYNTHESIS OF TEMPERATURE-TUNABLE PEPTIDE AND GOLD NANOPARTICLE HYBRID SPHERES GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2013-05-16 US disclosed
US-20120276002-A1 CONTRAST AGENT FOR OPTICAL IMAGING, USE THEREOF AND APPARATUS USING THE SAME KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2012-11-01 US disclosed
US-20120219495-A1 NOVEL TETRAAZA MACROCYCLIC COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2012-08-30 US disclosed
EP-2491953-A2 OPTICAL IMAGING CONTRAST AGENT, USE AND DEVICE THEREOF Kyungpook National University Industry- Academic Cooperation Foundation (KR) 2012-08-29 EP disclosed
EP-2476683-A2 NOVEL TETRA-AZA MACROCYCLIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF Kyungpook National University Industry- Academic Cooperation Foundation (KR) 2012-07-18 EP disclosed
US-20120087859-A1 NANOCARRIER HAVING ENHANCED SKIN PERMEABILITY, CELLULAR UPTAKE AND TUMOUR DELIVERY PROPERTIES GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2012-04-12 US disclosed
EP-2298929-A1 Sorting and immobilization system for nucleic acids using synthetic binding systems Nanogen Recognomics GmbH (DE) 2011-03-23 EP disclosed
CN-101925677-A Assay for detecting genetic abnormalities in genomic nucleic acids QUEST DIAGNOSTICS INVEST INC 2010-12-22 CN disclosed
EP-2218726-A1 Sorting and immobilization system for nucleic acids using synthetic binding systems Nanogen Recognomics GmbH (DE) 2010-08-18 EP disclosed
EP-1412518-B1 SORTING AND IMMOBILIZATION SYSTEM FOR NUCLEIC ACIDS USING SYNTHETIC BINDING SYSTEMS NANOGEN RECOGNOMICS GMBH (DE) 2010-05-12 EP disclosed
CN-101680023-A Methods for detecting methicillin-resistant s. aureus as well as primers, probes and kits for the same ROCHE DIAGNOSTICS GMBH 2010-03-24 CN disclosed
US-20090196937-A1 TEMPERATURE-SENSITIVE NANO-CARRIERS GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2009-08-06 US disclosed
EP-2082734-A2 Temperature-sensitive nano-carriers Gwangju Institute of Science and Technology (KR) 2009-07-29 EP disclosed
US-20070042386-A1 Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system NANOGEN, INC. 2007-02-22 US disclosed
CN-1735696-A Monitoring high-risk environments CARGILL INC (US) 2006-02-15 CN disclosed
US-20050208576-A1 Sorting and immobilization system for nucleic acids using synthetic binding systems NANOGEN RECOGNOMICS GMBH 2005-09-22 US disclosed
US-6911310-B2 Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system NANOGEN, INC. (US) 2005-06-28 US disclosed
US-6893822-B2 Enzymatic modification of a nucleic acid-synthetic binding unit conjugate NANOGEN RECOGNOMICS GMBH (DE) 2005-05-17 US disclosed
EP-1067134-B1 Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system NANOTRONICS INC (US) 2004-07-28 EP disclosed
EP-1412518-A2 SORTING AND IMMOBILIZATION SYSTEM FOR NUCLEIC ACIDS USING SYNTHETIC BINDING SYSTEMS Nanogen Recognomics GmbH (DE) 2004-04-28 EP disclosed
US-20030175702-A1 Sorting and immobilization system for nucleic acids using synthetic binding systems SANOFI-AVENTIS S.A. (FR) 2003-09-18 US disclosed
US-20030054361-A1 Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system NANOGEN, INC. (US) 2003-03-20 US disclosed
WO-2003008638-A2 SORTING AND IMMOBILIZATION SYSTEM FOR NUCLEIC ACIDS USING SYNTHETIC BIDNING SYSTEMS NANOGEN RECOGNOMICS GMBH (DE) 2003-01-30 WO disclosed
US-6416953-B1 BIOSENSOR COMPRISING PHOTONIC ENERGY SENSOR, POLYNUCLEOTIDE LINKED TO AT LEAST TWO DONOR CHROMOPHORES, SECOND POLYNUCLEOTIDE LINKED TO ACCEPTOR CHROMOPHORE POSITIONED BY LINKAGE AT DONOR-ACCEPTOR TRANSFER DISTANCE FROM DONOR NANOGEN, INC. 2002-07-09 US disclosed
EP-0620822-B1 HYBRIDIZATION OF POLYNUCLEOTIDES CONJUGATED WITH CHROMOPHORES AND FLUOROPHORES TO GENERATE DONOR-TO-DONOR ENERGY TRANSFER SYSTEM NANOTRONICS INC (US) 2001-05-30 EP disclosed
EP-1067134-A2 Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system NANOTRONICS, INC. (US) 2001-01-10 EP disclosed
US-6162603-A Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system NANOGEN, INC. (US) 2000-12-19 US disclosed
US-5849489-A Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system NANOGEN, INC. (US) 1998-12-15 US disclosed
US-5565322-A PHOTOELECTRIC DEVICES; DETECTORS; MEDICAL DIAGNOSIS NANOGEN, INC. (US) 1996-10-15 US disclosed
EP-0620822-A4 HYBRIDIZATION OF POLYNUCLEOTIDES CONJUGATED WITH CHROMOPHORES AND FLUOROPHORES TO GENERATE DONOR-TO-DONOR ENERGY TRANSFER SYSTEM. NANOTRONICS INC (US) 1996-01-10 EP disclosed
EP-0620822-A1 HYBRIDIZATION OF POLYNUCLEOTIDES CONJUGATED WITH CHROMOPHORES AND FLUOROPHORES TO GENERATE DONOR-TO-DONOR ENERGY TRANSFER SYSTEM NANOTRONICS, INC. (US) 1994-10-26 EP disclosed
WO-1993009128-A1 HYBRIDIZATION OF POLYNUCLEOTIDES CONJUGATED WITH CHROMOPHORES AND FLUOROPHORES TO GENERATE DONOR-TO-DONOR ENERGY TRANSFER SYSTEM NANOTRONICS, INC. (US) 1993-05-13 WO disclosed
WO-1993009128-A1 HYBRIDIZATION OF POLYNUCLEOTIDES CONJUGATED WITH CHROMOPHORES AND FLUOROPHORES TO GENERATE DONOR-TO-DONOR ENERGY TRANSFER SYSTEM NANOTRONICS, INC. (US) 1993-05-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150291608-A1 NOVEL TETRAAZA MACROCYCLIC COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF TBCA, NBAS, BMP2 KMT2A 1768/4885ALDH1A1 3814/4885KDM4E 4705/4885
US-20170371042-A1 CONTRAST AGENT FOR OPTICAL IMAGING, USE THEREOF AND APPARATUS USING THE SAME SLCO2A1, SLCO1A2, SLCO4C1 KMT2A 3895/4885ALDH1A1 1571/4885KDM4E 4240/4885
US-20120276002-A1 CONTRAST AGENT FOR OPTICAL IMAGING, USE THEREOF AND APPARATUS USING THE SAME SLCO2A1, SLCO1A2, SLCO4C1 KMT2A 3895/4885ALDH1A1 1571/4885KDM4E 4240/4885
US-20120219495-A1 NOVEL TETRAAZA MACROCYCLIC COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF TBCA, NBAS, BMP2 KMT2A 1768/4885ALDH1A1 3814/4885KDM4E 4705/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.