Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrene SCHEMBL1061899 | 1.00 | KMT2A (0.38) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL5349813 | 0.95 | AKR1C3 (0.35) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| Butyric Acid SCHEMBL1284593 | 0.81 | KMT2A (0.47) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| Pyrene SCHEMBL29695823 | 0.80 | KMT2A (0.50) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL1133422 | 0.75 | KMT2A (0.54) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| Pyrene SCHEMBL5502107 | 0.73 | KMT2A (0.46) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL5352784 | 0.72 | ALDH1A1 (0.36) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| Pyrene SCHEMBL9435802 | 0.69 | HPGD (0.59) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| Pyrene SCHEMBL38210 | 0.69 | HPGD (0.59) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| Pyrene SCHEMBL30069714 | 0.69 | HPGD (0.59) | KMT2AMEN1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115315515-A | Engineered GYRI-like mutein aptamers and related methods | 跨界科技公司 | 2022-11-08 | — | — | CN | disclosed |
| WO-2021263188-A9 | LIVE CELL ENGAGEMENT ASSAY | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2022-06-09 | — | — | WO | disclosed |
| WO-2021263188-A1 | LIVE CELL ENGAGEMENT ASSAY | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2021-12-30 | — | — | WO | disclosed |
| EP-1740100-A1 | XANTHENE DYES | Biosearch Technologies, Inc. (US) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005102176-A1 | XANTHENE DYES | BIOSEARCH TECHNOLOGIES, INC. (US) | 2005-11-03 | — | — | WO | disclosed |