Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.78 |
| ▸ | NPC1 | O15118 | 1/20 | 0.78 |
| ▸ | RAB9A | P51151 | 1/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.76 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.47 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2072157 | 0.88 | SMN1; SMN2 (1.00) | SMN1; SMN2NPC1RAB9AKDM4ETDP1 | |
| SCHEMBL11336688 | 0.86 | SMN1; SMN2 (0.78) | SMN1; SMN2NPC1RAB9AKDM4ETDP1 | |
| SCHEMBL9004662 | 0.80 | KDM4E (0.63) | SMN1; SMN2NPC1RAB9AKDM4ETDP1 | |
| SCHEMBL1272747 | 0.79 | SMN1; SMN2 (0.67) | SMN1; SMN2NPC1RAB9AKDM4ETDP1 | |
| SCHEMBL10367346 | 0.78 | SMN1; SMN2 (0.71) | SMN1; SMN2NPC1RAB9AKDM4ETDP1 | |
| SCHEMBL28795915 | 0.77 | SMN1; SMN2 (0.69) | SMN1; SMN2NPC1RAB9AKDM4ETDP1 | |
| SCHEMBL1272745 | 0.75 | SMN1; SMN2 (0.67) | SMN1; SMN2NPC1RAB9AKDM4ETDP1 | |
| SCHEMBL30539543 | 0.75 | PSMB8 (0.58) | SMN1; SMN2NPC1RAB9AKDM4ETDP1 | |
| SCHEMBL29092798 | 0.75 | PSMB8 (0.58) | SMN1; SMN2NPC1RAB9AKDM4ETDP1 | |
| SCHEMBL19866033 | 0.74 | ALDH1A1 (0.70) | SMN1; SMN2NPC1RAB9AKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4260770-A | Naphtholactam dyes | CIBA-GEIGY AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |
| US-4256896-A | THIAZOLE, IMIDAZOLINE, AND OXAZOLINE DYES; DISPERSE DYES; ANIONIC DYES; TEXTILES | CIBA-GEIGY AKTIENGESELLSCHAFT (DE) | 1981-03-17 | — | — | US | disclosed |