Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.71 |
| ▸ | RAB9A | P51151 | 3/20 | 0.71 |
| ▸ | NPC1 | O15118 | 2/20 | 0.71 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.59 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.59 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11327660 | 0.92 | SMN1; SMN2 (0.66) | SMN1; SMN2RAB9ANPC1UBE2TASIC3 | |
| SCHEMBL28795915 | 0.87 | SMN1; SMN2 (0.69) | SMN1; SMN2RAB9ANPC1UBE2TASIC3 | |
| SCHEMBL1272747 | 0.86 | SMN1; SMN2 (0.67) | SMN1; SMN2RAB9ANPC1UBE2TASIC3 | |
| SCHEMBL1272745 | 0.86 | SMN1; SMN2 (0.67) | SMN1; SMN2RAB9ANPC1UBE2TASIC3 | |
| SCHEMBL2072157 | 0.83 | SMN1; SMN2 (1.00) | SMN1; SMN2RAB9ANPC1UBE2TASIC3 | |
| SCHEMBL10370401 | 0.82 | KDM4E (0.65) | SMN1; SMN2RAB9ANPC1UBE2TASIC3 | |
| SCHEMBL244156 | 0.79 | UBE2T (0.66) | SMN1; SMN2RAB9ANPC1UBE2TASIC3 | |
| SCHEMBL11336688 | 0.78 | SMN1; SMN2 (0.78) | SMN1; SMN2RAB9ANPC1UBE2TASIC3 | |
| SCHEMBL11334684 | 0.78 | SMN1; SMN2 (0.78) | SMN1; SMN2RAB9ANPC1UBE2TASIC3 | |
| SCHEMBL226465 | 0.78 | UBE2T (0.70) | SMN1; SMN2RAB9ANPC1UBE2TASIC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0165537-B1 | PROCESS FOR THE PREPARATION OF HETEROARYLOXYACETAMIDES | BAYER AG (DE) | 1990-01-17 | — | — | EP | claimed |