Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 2/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PPARD | Q03181 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PTPRB | P23467 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11332023 | 0.88 | MIF (0.40) | MIFLDHAACACBESR1ESR2 | |
| SCHEMBL15729872 | 0.88 | LDHA (0.53) | MIFLDHAACACBPPARGPPARA | |
| SCHEMBL27323338 | 0.82 | MIF (0.62) | MIFESR1ESR2 | |
| SCHEMBL18057033 | 0.82 | MIF (0.43) | MIFLDHAACACBESR1ESR2 | |
| SCHEMBL5399978 | 0.80 | MIF (0.56) | MIFPPARGPPARA | |
| SCHEMBL135996 | 0.80 | MIF (0.56) | MIFPPARGPPARA | |
| SCHEMBL820965 | 0.80 | MIF (0.56) | MIFPPARGPPARA | |
| SCHEMBL11924843 | 0.80 | MIF (0.46) | MIFLDHAACACBESR1ESR2 | |
| SCHEMBL22767838 | 0.76 | PPARG (0.49) | PPARGPPARDPPARA | |
| SCHEMBL27352895 | 0.75 | LDHA (0.63) | LDHAACACBPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4243605-A | RADIOIMMUNOASSAY, LABELS | UNION CARBIDE CORPORATION (US) | 1981-01-06 | — | — | US | disclosed |
| US-4130576-A | Method for preparing isocyanates from halosilyl carbamates | UNION CARBIDE CORPORATION (US) | 1978-12-19 | — | — | US | disclosed |
| US-4115539-A | RADIOIMMUNOASSAY, REACTION PRODUCT WITH ISOCYANATES | UNION CARBIDE CORPORATION (US) | 1978-09-19 | — | — | US | disclosed |
| US-4064151-A | ISOCYANATE INTERMEDIATES | UNITED CARBIDE CORPORATION (US) | 1977-12-20 | — | — | US | disclosed |