Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL135996 | 1.00 | MIF (0.56) | MIFATMANPEPCYP2C9CYP2C19 | |
| SCHEMBL5399978 | 1.00 | MIF (0.56) | MIFATMANPEPCYP2C9CYP2C19 | |
| SCHEMBL15729872 | 0.86 | LDHA (0.53) | MIFALDH1A1PPARGPPARA | |
| SCHEMBL4700347 | 0.86 | MIF (0.54) | MIFATMANPEPCYP2C9CYP2C19 | |
| SCHEMBL7882113 | 0.86 | MMP8 (0.51) | MIFALDH1A1HSD17B10POLBMEN1 | |
| SCHEMBL27323338 | 0.86 | MIF (0.62) | MIFMEN1KMT2ANPC1RAB9A | |
| SCHEMBL279730 | 0.86 | MMP8 (0.51) | MIFALDH1A1HSD17B10POLBMEN1 | |
| SCHEMBL27883366 | 0.85 | TSHR (0.48) | MIFALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL7266856 | 0.84 | ALDH1A1 (0.46) | MIFALDH1A1KMT2ALMNANPC1 | |
| SCHEMBL7266845 | 0.84 | ALDH1A1 (0.46) | MIFALDH1A1KMT2ALMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304516-A | Compounds with unconventional chromophores, their preparation and use | 四川大学 | 2022-11-08 | — | — | CN | claimed |
| CN-115232130-A | APN and AKT double-target-point inhibitor and preparation method and application thereof | 山东大学 | 2022-10-25 | — | — | CN | claimed |
| CN-115304516-B | Compounds with unconventional chromophores, their preparation and use | 四川大学 | 2024-04-30 | — | — | CN | disclosed |
| CN-115232130-B | APN and AKT double-target inhibitor and preparation method and application thereof | 山东大学 | 2024-01-12 | — | — | CN | disclosed |
| CN-115232130-A | APN and AKT double-target-point inhibitor and preparation method and application thereof | 山东大学 | 2022-10-25 | — | — | CN | disclosed |
| CN-107459511-A | Ketone compounds of 4 imino group oxazolidine of anti-enteric virus71 (EV71) 2 and its production and use | 南开大学 | 2017-12-12 | — | — | CN | disclosed |
| CN-103130710-B | Anti-enteric virus71 (EV71) hexanolactam aldehyde compound and its production and use | NANKAI UNIVERSITY (CN) | 2015-12-16 | — | — | CN | disclosed |
| CN-103145608-B | Anti-enteric virus71 (EV71) hexanolactam compounds and its production and use | NANKAI UNIVERSITY (CN) | 2015-09-02 | — | — | CN | disclosed |
| CN-103145608-A | Anti-enterovirus 71 (EV71) caprolactam compounds, and preparation method and application thereof | UNIV NANKAI | 2013-06-12 | — | — | CN | disclosed |
| CN-103130710-A | Anti-enterovirus 71 (EV 71) caprolactam aldehyde compound and preparation method and purpose thereof | UNIV NANKAI | 2013-06-05 | — | — | CN | disclosed |
| EP-2389399-A2 | FUNCTIONALIZED POLYURETHANE RESIN, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF | Construction Research & Technology GmbH (DE) | 2011-11-30 | — | — | EP | disclosed |
| US-20010056100-A1 | Carboxylic acid derivatives as IP antagonists | SYNTEX (U.S.A.) LLC | 2001-12-27 | — | — | US | disclosed |
| WO-2001068591-A1 | CARBOXYLIC ACID DERIVATIVES AS IP ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2001-09-20 | — | — | WO | disclosed |
| EP-1126833-A2 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2001-08-29 | — | — | EP | disclosed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | disclosed |
| US-5492896-A | TREATING CYTOMEGALO VIRUS INFECTIONS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-02-20 | — | — | US | disclosed |
| EP-0490566-B1 | Preparation and use of N-iodopropargyl oxycarbonyl amino acid esters and derivatives as antimicrobial agents | ROHM & HAAS (US) | 1994-10-12 | — | — | EP | disclosed |
| US-5209930-A | PREPARATION AND USE OF N-IODOPROPARGYL OXYCARBONYL AMINO ACID ESTERS AND DERIVATIVES AS ANTIMICROBIAL AGENTS | ROHM AND HAAS COMPANY (US) | 1993-05-11 | — | — | US | disclosed |
| EP-0490566-A1 | Preparation and use of N-iodopropargyl oxycarbonyl amino acid esters and derivatives as antimicrobial agents | ROHM AND HAAS COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |
| EP-0207358-A2 | Growth-promoting agent | BAYER AG (DE) | 1987-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010056100-A1 | Carboxylic acid derivatives as IP antagonists | GABRP, GPBAR1, FFAR1 | MIF 328/4885ATM 4352/4885ANPEP 1737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.