SCHEMBL11336752

SCHEMBL11336752

CC(=O)SCC(CCCN)C(=O)N[C@@H](CC(=O)O)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 2/20 0.56
GNPAT O15228 1/20 0.44
MME P08473 3/20 0.39
FOLH1 Q04609 1/20 0.37
ENPEP Q07075 5/20 0.35
BMP1 P13497 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11331433 0.88 CPB2 (0.57) CPB2GNPATMMEFOLH1
SCHEMBL11321753 0.86 CPB2 (0.55) CPB2MMEFOLH1
SCHEMBL11333852 0.85 CPB2 (0.53) CPB2GNPATMMEFOLH1BMP1
SCHEMBL11334875 0.85 CPB2 (0.53) CPB2
SCHEMBL11433243 0.82 CPB2 (0.64) CPB2GNPATFOLH1
SCHEMBL26352069 0.82 GNPAT (0.46) CPB2GNPATMMEFOLH1ENPEP
SCHEMBL11326734 0.81 GNPAT (0.50) CPB2GNPATMME
SCHEMBL11333911 0.79 CPB2 (0.57) CPB2GNPATMMEFOLH1BMP1
SCHEMBL10918805 0.78 CPB2 (0.87) CPB2
SCHEMBL11329932 0.78 CPB2 (0.57) CPB2MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4284779-A Amino acid derivatives E. R. SQUIBB & SONS, INC. (US) 1981-08-18 US disclosed
US-4284780-A Amino acid derivatives E. R. SQUIBB & SONS, INC. (US) 1981-08-18 US disclosed
US-4179434-A Amino acid derivatives E. R. SQUIBB & SONS, INC. (US) 1979-12-18 US disclosed
US-4177277-A INHIBITION OF ANGIOTENSIN-CONVERTING ENZYME E. R. SQUIBB & SONS, INC. (US) 1979-12-04 US disclosed
US-4165320-A Amino acid derivatives E. R. SQUIBB & SONS, INC. (US) 1979-08-21 US disclosed
US-4156786-A Amino acid derivatives E. R. SQUIBB & SONS, INC. (US) 1979-05-29 US disclosed
US-4154960-A Amino acid derivatives E. R. SQUIBB & SONS, INC. (US) 1979-05-15 US disclosed
US-4154946-A Amino mercapto substituted acylamino acids E. R. SQUIBB & SONS, INC. (US) 1979-05-15 US disclosed
US-4146611-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1979-03-27 US disclosed
US-4129571-A Amino acid derivatives E. R. SQUIBB & SONS, INC. (US) 1978-12-12 US disclosed
US-4113715-A Amino acid derivatives E. R. SQUIBB & SONS, INC. (US) 1978-09-12 US disclosed