Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 8/20 | 0.64 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
| ▸ | GNPAT | O15228 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.40 |
| ▸ | ECE1 | P42892 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11331433 | 0.83 | CPB2 (0.57) | CPB2FOLH1GNPAT | |
| SCHEMBL11333852 | 0.83 | CPB2 (0.53) | CPB2FOLH1SLC6A5GNPATECE1 | |
| SCHEMBL11334875 | 0.83 | CPB2 (0.53) | CPB2 | |
| SCHEMBL11336752 | 0.82 | CPB2 (0.56) | CPB2FOLH1GNPAT | |
| SCHEMBL11321753 | 0.81 | CPB2 (0.55) | CPB2FOLH1 | |
| SCHEMBL11432087 | 0.81 | BMP1 (0.44) | CPB2FOLH1GNPATECE1 | |
| SCHEMBL11560458 | 0.80 | CPB2 (0.41) | CPB2FOLH1GNPAT | |
| SCHEMBL2167433 | 0.79 | FOLH1 (0.55) | CPB2FOLH1SLC6A5GNPATSIRT6 | |
| SCHEMBL29396098 | 0.77 | GNPAT (0.60) | CPB2FOLH1SLC6A5GNPATSIRT6 | |
| SCHEMBL29396725 | 0.77 | GNPAT (0.60) | CPB2FOLH1SLC6A5GNPATSIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4228077-A | N-[2-(mercaptoalkyl)-3-mercaptoalkanoyl]-l-tryptophanes | E. R. SQUIBB & SONS, INC. (US) | 1980-10-14 | — | — | US | disclosed |
| US-4206121-A | ANGIOTENSIN, ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1980-06-03 | — | — | US | disclosed |
| US-4178291-A | HYPOTENSIVE AGENTS, ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1979-12-11 | — | — | US | disclosed |
| US-4176235-A | ANGIOTENSIN COVERTING ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1979-11-27 | — | — | US | disclosed |
| US-4175199-A | Substituted acyl derivatives of amino acids | E. R. SQUIBB & SONS, INC. (US) | 1979-11-20 | — | — | US | disclosed |
| US-4154936-A | ENZYME INHIBITORS, HYPOTENSIVE | E. R. SQUIBB & SONS, INC. (US) | 1979-05-15 | — | — | US | disclosed |
| US-4140864-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1979-02-20 | — | — | US | disclosed |
| US-4116962-A | ANGIOTENSIN CONVERTING ENXYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1978-09-26 | — | — | US | disclosed |