SCHEMBL11336847

SCHEMBL11336847

NC(=O)[C@@H]1CCCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1CCC(=O)N1

nearest known ligand 0.68

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TRHR P34981 6/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Protirelin SCHEMBL8364920 0.97 TRHR (0.71) TRHR
Protirelin SCHEMBL20659679 0.97 TRHR (0.71) TRHR
Protirelin SCHEMBL14280929 0.97 TRHR (0.71) TRHR
Protirelin SCHEMBL11798811 0.97 TRHR (0.71) TRHR
Protirelin SCHEMBL2182035 0.97 TRHR (0.71) TRHR
Protirelin SCHEMBL11669085 0.94 TRHR (0.68) TRHR
SCHEMBL10589322 0.93 TRHR (0.76) TRHR
Protirelin SCHEMBL10760265 0.93 TRHR (0.65) TRHR
SCHEMBL11820778 0.92 TRHR (0.57) TRHR
SCHEMBL11815435 0.92 TRHR (0.57) TRHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4299821-A HYPOTHERMIC AGENTS, TREATMENT OF NARCOLEPSY RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 1981-11-10 — — US disclosed
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