Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11337008 | 1.00 | HSD17B10 (0.44) | HSD17B10KDM4ETDP1GAADDB1 | |
| SCHEMBL11337006 | 1.00 | HSD17B10 (0.44) | HSD17B10KDM4ETDP1GAADDB1 | |
| SCHEMBL505836 | 0.87 | CHRM1 (0.47) | DDB1CRBNHTTNPC1RAB9A | |
| SCHEMBL9721473 | 0.87 | CHRM1 (0.47) | DDB1CRBNHTTNPC1RAB9A | |
| SCHEMBL9721501 | 0.87 | CHRM1 (0.47) | DDB1CRBNHTTNPC1RAB9A | |
| SCHEMBL9721480 | 0.87 | CHRM1 (0.47) | DDB1CRBNHTTNPC1RAB9A | |
| SCHEMBL9721512 | 0.87 | CHRM1 (0.47) | DDB1CRBNHTTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7619875 | 0.85 | MMP2 (0.61) | NPC1 | |
| Hydrochloric Acid SCHEMBL7619870 | 0.85 | MMP2 (0.61) | NPC1 | |
| SCHEMBL9196176 | 0.85 | PRKCE (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4254135-A | ANTIDEPRESSANT | A. H. ROBINS COMPANY, INC. (US) | 1981-03-03 | — | — | US | disclosed |