Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCE | Q02156 | 16/20 | 0.49 |
| ▸ | PRKCB | P05771 | 14/20 | 0.49 |
| ▸ | PRKCA | P17252 | 13/20 | 0.49 |
| ▸ | PRKCH | P24723 | 8/20 | 0.49 |
| ▸ | PRKCD | Q05655 | 8/20 | 0.49 |
| ▸ | PRKCG | P05129 | 7/20 | 0.49 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.49 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | KDM5A | P29375 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 4/20 | 0.42 |
| ▸ | PRKACG | P22612 | 3/20 | 0.42 |
| ▸ | PRKACB | P22694 | 3/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11337008 | 0.85 | HSD17B10 (0.44) | — | |
| SCHEMBL11337013 | 0.85 | HSD17B10 (0.44) | — | |
| SCHEMBL11337006 | 0.85 | HSD17B10 (0.44) | — | |
| SCHEMBL16031870 | 0.83 | MLYCD (0.45) | CYP3A4 | |
| SCHEMBL16031871 | 0.83 | MLYCD (0.45) | CYP3A4 | |
| SCHEMBL16031866 | 0.83 | MLYCD (0.45) | CYP3A4 | |
| SCHEMBL14140665 | 0.82 | ALDH1A1 (0.47) | MPOCYP3A4GFERPRKCI | |
| Hydrochloric Acid SCHEMBL7619870 | 0.78 | MMP2 (0.61) | — | |
| Hydrochloric Acid SCHEMBL7619875 | 0.78 | MMP2 (0.61) | — | |
| SCHEMBL9201097 | 0.77 | FAAH (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687249-A1 | BALANOIDS | ELI LILLY AND COMPANY (US) | 1995-12-20 | — | — | EP | disclosed |
| WO-1994020062-A2 | BALANOIDS AS PROTEIN KINASE C INHIBITORS | ELI LILLY AND COMPANY (US) | 1994-09-15 | — | — | WO | disclosed |