Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 14/20 | 0.50 |
| ▸ | CTSK | P43235 | 14/20 | 0.50 |
| ▸ | CTSL | P07711 | 4/20 | 0.41 |
| ▸ | CTSB | P07858 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11336790 | 0.78 | — | — | |
| SCHEMBL6871698 | 0.77 | CTSS (0.47) | CTSSCTSKCTSLCTSBMCL1 | |
| SCHEMBL9227162 | 0.76 | — | — | |
| SCHEMBL9967749 | 0.73 | — | — | |
| SCHEMBL10803781 | 0.72 | CTSS (0.44) | CTSSCTSKCTSLCTSBMCL1 | |
| SCHEMBL15259327 | 0.71 | CTSS (0.46) | CTSSCTSKCTSLCTSBMCL1 | |
| SCHEMBL8371217 | 0.71 | HDAC7 (0.54) | CTSSCTSKCTSLCTSB | |
| SCHEMBL11291749 | 0.71 | TSHR (0.36) | — | |
| SCHEMBL2910344 | 0.71 | CTSS (0.50) | CTSSCTSKCTSLCTSBCTSC | |
| SCHEMBL4865683 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4260624-A | Fungicidal 2-substituted-3-oxa-3a lambda4,4-dithia-6-chloro-1,5-diazapentalene | CHEVRON RESEARCH COMPANY (US) | 1981-04-07 | — | — | US | disclosed |