⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9233843 | 0.78 | — | — | |
| SCHEMBL11337152 | 0.76 | CTSS (0.50) | — | |
| SCHEMBL11291749 | 0.76 | TSHR (0.36) | — | |
| SCHEMBL4865683 | 0.75 | — | — | |
| SCHEMBL9226670 | 0.75 | — | — | |
| SCHEMBL7346035 | 0.74 | — | — | |
| SCHEMBL18932272 | 0.73 | — | — | |
| SCHEMBL605099 | 0.73 | — | — | |
| SCHEMBL11571232 | 0.71 | ALDH1A1 (0.42) | — | |
| SCHEMBL11261611 | 0.71 | CRBN (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5451438-A | Molding material useful for absorption, separation and immobilization of bioactive materials | BIOMATERIAL RESEARCH INSTITUTE CO., LTD. (JP) | 1995-09-19 | — | — | US | disclosed |
| EP-0621301-A1 | ACYLAMIDOMETHYLATED POLYSULFONE AND PROCESS FOR PRODUCING THE SAME | BIOMATERIAL RESEARCH INSTITUTE CO., LTD. (JP) | 1994-10-26 | — | — | EP | disclosed |