Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7136183 | 0.72 | — | — | |
| SCHEMBL2702676 | 0.71 | ALDH1A1 (0.33) | MAOAMAOBTDP1MAPK1ALDH1A1 | |
| SCHEMBL7913634 | 0.68 | MAOA (0.59) | MAOAMAOBHSD17B3TDP1MEN1 | |
| SCHEMBL7102907 | 0.68 | — | — | |
| SCHEMBL5835186 | 0.60 | MAOA (0.45) | MAOAMAOBHSD17B3TDP1MEN1 | |
| SCHEMBL31344214 | 0.60 | MAOA (0.50) | MAOAMAOBHSD17B3TDP1MEN1 | |
| SCHEMBL20719022 | 0.59 | MAOA (0.34) | MAOAMAOBHSD17B3TDP1MEN1 | |
| SCHEMBL31689772 | 0.59 | — | — | |
| SCHEMBL2398119 | 0.58 | — | — | |
| SCHEMBL2729732 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117088921-A | Metal complexes of bicycloalkyl-pyridine skeleton, intermediates, synthesis and catalyst compositions | 河北农业大学 | 2023-11-21 | — | — | CN | disclosed |
| EP-4265621-A1 | PYRROLE DERIVATIVE, AND PREPARATION METHOD AND USE THEREFOR | Shenzhen Sungening Bio-Medical Co., Ltd. (CN) | 2023-10-25 | — | — | EP | disclosed |
| CN-115720578-A | Tricyclic derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-02-28 | — | — | CN | disclosed |
| CN-110386954-A | Containing asymmetric condensed ring pyridine imine base complex and the preparation method and application thereof | 中国科学院化学研究所 | 2019-10-29 | — | — | CN | disclosed |
| CN-110386954-A | Containing asymmetric condensed ring pyridine imine base complex and the preparation method and application thereof | 中国科学院化学研究所 | 2019-10-29 | — | — | CN | disclosed |
| EP-2285820-A1 | INTERCALATING TRIPLEXES AND DUPLEXES USING ARYL NAPHTHOIMIDAZOL AND PROCESS FOR THE PREPARATION THEREOF | Syddansk Universitet (DK) | 2011-02-23 | — | — | EP | disclosed |
| WO-2009135890-A1 | INTERCALATING TRIPLEXES AND DUPLEXES USING ARYL NAPHTHOIMIDAZOL AND PROCESS FOR THE PREPARATION THEREOF | SYDDANSK UNIVERSITET (DK) | 2009-11-12 | — | — | WO | disclosed |