SCHEMBL11338134

SCHEMBL11338134

CCCCCCCCCCCCOC(=O)c1cc(N)c(Cl)c(N)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 8/20 0.61
MAPT P10636 3/20 0.61
ALDH1A1 P00352 2/20 0.61
NPC1 O15118 1/20 0.61
RAB9A P51151 1/20 0.61
AKR1C4 P17516 1/20 0.61
AKR1C3 P42330 1/20 0.61
AKR1C2 P52895 1/20 0.61
AKR1C1 Q04828 1/20 0.61
KDM4E B2RXH2 1/20 0.55
POLB P06746 1/20 0.55
HSD17B10 Q99714 1/20 0.55
ATM Q13315 2/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
LMNA P02545 2/20 0.55
GAA P10253 1/20 0.55
TSHR P16473 2/20 0.53
CYP1A2 P05177 1/20 0.53
CYP3A4 P08684 1/20 0.53
CYP2C9 P11712 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31426447 0.94 ESR1 (0.65) ESR1MAPTALDH1A1NPC1RAB9A
SCHEMBL9598313 0.87 LMNA (0.51) ESR1MAPTALDH1A1NPC1RAB9A
SCHEMBL8897849 0.84 ALDH1A1 (0.65) ESR1MAPTALDH1A1NPC1RAB9A
SCHEMBL2892370 0.84 ALDH1A1 (0.65) ESR1MAPTALDH1A1NPC1RAB9A
SCHEMBL10416281 0.84 ALDH1A1 (0.65) ESR1MAPTALDH1A1NPC1RAB9A
SCHEMBL11116165 0.84 ALDH1A1 (0.65) ESR1MAPTALDH1A1NPC1RAB9A
SCHEMBL9355632 0.84 ESR1 (0.77) ESR1MAPTALDH1A1NPC1RAB9A
SCHEMBL22289827 0.84 ESR1 (0.77) ESR1MAPTALDH1A1NPC1RAB9A
SCHEMBL22289766 0.84 ESR1 (0.77) ESR1MAPTALDH1A1NPC1RAB9A
SCHEMBL22289841 0.84 ESR1 (0.77) ESR1MAPTALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113892063-A Elastic body for blade and cleaning blade using the same 阪东化学株式会社 2022-01-04 CN disclosed
US-4248961-A YELLOW COUPLER ACHIEVING GOOD COLOR DENSITY CIBA-GEIGY AG (CH) 1981-02-03 US disclosed