Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | HPSE | Q9Y251 | 7/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.44 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | CBX7 | O95931 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | PRKCG | P05129 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PRKCB | P05771 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10909172 | 0.93 | LMNA (0.43) | TRPV1HPSEHSD17B10PRMT1MEN1 | |
| SCHEMBL11340304 | 0.87 | CA12 (0.41) | TRPV1HSD17B10PRMT1MEN1KMT2A | |
| SCHEMBL11347884 | 0.85 | KMT2A (0.49) | TRPV1HPSEHSD17B10PRMT1MEN1 | |
| SCHEMBL11341037 | 0.85 | KMT2A (0.52) | TRPV1HPSEHSD17B10PRMT1MEN1 | |
| SCHEMBL11339146 | 0.84 | RECQL (0.54) | HPSEHSD17B10PRMT1MEN1KMT2A | |
| SCHEMBL11340386 | 0.84 | KMT2A (0.53) | TRPV1HPSEHSD17B10PRMT1MEN1 | |
| SCHEMBL11342415 | 0.83 | PRMT1 (0.42) | TRPV1HPSEHSD17B10PRMT1MEN1 | |
| SCHEMBL10823528 | 0.83 | IDH1 (0.54) | MEN1KMT2A | |
| SCHEMBL11344331 | 0.83 | HPSE (0.47) | TRPV1HPSEHSD17B10PRMT1MEN1 | |
| SCHEMBL11346722 | 0.83 | RECQL (0.52) | TRPV1HPSEHSD17B10PRMT1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4297372-A | ANTIARTHRITIC AGENTS; COLLAGENASE AND PROTEOLYTIC ENZYME INHIBITORS; BONE, SKIN, AND ORAL DISORDERS | AMERICAN CYANAMID COMPANY (US) | 1981-10-27 | — | — | US | disclosed |
| EP-0013784-A1 | C-Substituted naphthalenemonosulfonic ureides, process for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1980-08-06 | — | — | EP | disclosed |