Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.40 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.40 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10907614 | 0.93 | LMNA (0.41) | POLBKMT2AMEN1LMNATSHR | |
| SCHEMBL11338535 | 0.87 | TRPV1 (0.46) | POLBKMT2AMEN1ALOX15PRMT1 | |
| SCHEMBL11347713 | 0.84 | KCNJ6 (0.42) | CA12CA1CA2CA9POLB | |
| SCHEMBL11344807 | 0.82 | TIMP3 (0.48) | CA12CA1CA2CA9POLB | |
| SCHEMBL10823556 | 0.81 | IDH1 (0.55) | KMT2AMEN1 | |
| SCHEMBL11350051 | 0.81 | KMT2A (0.53) | POLBKMT2AMEN1PRMT1LMNA | |
| SCHEMBL10909172 | 0.80 | LMNA (0.43) | POLBKMT2AMEN1PRMT1LMNA | |
| SCHEMBL11345504 | 0.80 | KCNJ6 (0.42) | CA12CA1CA2CA9POLB | |
| SCHEMBL11347958 | 0.79 | PRMT1 (0.53) | CA12CA1CA2CA9POLB | |
| SCHEMBL11349148 | 0.79 | DHODH (0.43) | CA12CA1CA2CA9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4297372-A | ANTIARTHRITIC AGENTS; COLLAGENASE AND PROTEOLYTIC ENZYME INHIBITORS; BONE, SKIN, AND ORAL DISORDERS | AMERICAN CYANAMID COMPANY (US) | 1981-10-27 | — | — | US | disclosed |