Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 9/20 | 0.53 |
| ▸ | HSD17B2 | P37059 | 9/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GPX4 | P36969 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24011585 | 0.86 | HSD17B1 (0.53) | HSD17B1HSD17B2TP53SIGMAR1ALDH1A1 | |
| SCHEMBL31425823 | 0.86 | HSD17B1 (0.53) | HSD17B1HSD17B2TP53SIGMAR1ALDH1A1 | |
| SCHEMBL95584 | 0.84 | HSD17B1 (0.51) | HSD17B1HSD17B2TP53SIGMAR1ALDH1A1 | |
| SCHEMBL9674499 | 0.84 | HSD17B1 (0.51) | HSD17B1HSD17B2TP53SIGMAR1ALDH1A1 | |
| SCHEMBL11661832 | 0.84 | ALDH1A1 (0.60) | HSD17B1HSD17B2TP53SIGMAR1ALDH1A1 | |
| SCHEMBL28541364 | 0.83 | HSD17B1 (0.50) | HSD17B1HSD17B2TP53SIGMAR1ALDH1A1 | |
| SCHEMBL23222221 | 0.83 | ALDH1A1 (0.51) | HSD17B1HSD17B2TP53SIGMAR1ALDH1A1 | |
| SCHEMBL11676115 | 0.83 | HSD17B1 (0.50) | HSD17B1HSD17B2TP53SIGMAR1ALDH1A1 | |
| SCHEMBL12164167 | 0.81 | HSD17B1 (0.49) | HSD17B1HSD17B2TP53SIGMAR1ALDH1A1 | |
| SCHEMBL11398353 | 0.81 | HTT (0.39) | TP53HTTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0037524-A1 | Substituted acetanilides, process for their preparation and their utilization as herbicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1981-10-14 | — | — | EP | disclosed |