Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CPB1 | P15086 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | HK1 | P19367 | 1/20 | 0.39 |
| ▸ | HK2 | P52789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11338875 | 1.00 | LMNA (0.48) | LMNAKMT2ALGALS8ALDH1A1CTSB | |
| SCHEMBL10618215 | 0.90 | LMNA (0.60) | LMNAKMT2AALDH1A1POLBTSHR | |
| SCHEMBL13466026 | 0.90 | LMNA (0.60) | LMNAKMT2AALDH1A1POLBTSHR | |
| SCHEMBL12837364 | 0.90 | LMNA (0.60) | LMNAKMT2AALDH1A1POLBTSHR | |
| SCHEMBL10618219 | 0.90 | LMNA (0.60) | LMNAKMT2AALDH1A1POLBTSHR | |
| SCHEMBL11322337 | 0.87 | LMNA (0.54) | LMNAKMT2ALGALS8ALDH1A1CTSB | |
| SCHEMBL11325557 | 0.87 | LMNA (0.54) | LMNAKMT2ALGALS8ALDH1A1CTSB | |
| SCHEMBL20202240 | 0.82 | HK1 (0.56) | LMNAKMT2ALGALS8TSHRHK1 | |
| SCHEMBL20207081 | 0.82 | HK1 (0.56) | LMNAKMT2ALGALS8TSHRHK1 | |
| SCHEMBL10618179 | 0.82 | LMNA (0.55) | LMNAKMT2AALDH1A1CTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251515-A | ANTITUMOR AGENTS, TREATMENT OF LEUKEMIA | SUAMI T | 1981-02-17 | — | — | US | disclosed |