Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.41 |
| ▸ | CPB1 | P15086 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.40 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11325557 | 1.00 | LMNA (0.54) | LMNALGALS8KMT2APOLBMMP9 | |
| SCHEMBL11322341 | 0.91 | LMNA (0.58) | LMNALGALS8KMT2APOLBMMP9 | |
| SCHEMBL11338877 | 0.87 | LMNA (0.48) | LMNALGALS8KMT2APOLBCPB1 | |
| SCHEMBL11338875 | 0.87 | LMNA (0.48) | LMNALGALS8KMT2APOLBCPB1 | |
| SCHEMBL8712020 | 0.86 | LMNA (0.53) | LMNALGALS8KMT2APOLBMMP9 | |
| SCHEMBL12501263 | 0.85 | LGALS8 (0.64) | LGALS8LGALS3CPB1LGALS9LGALS7; LGALS7B | |
| SCHEMBL12501267 | 0.85 | LGALS8 (0.64) | LGALS8LGALS3CPB1LGALS9LGALS7; LGALS7B | |
| SCHEMBL2007087 | 0.84 | LMNA (0.76) | LMNAKMT2APOLBMMP12ALDH1A1 | |
| SCHEMBL2007088 | 0.84 | LMNA (0.76) | LMNAKMT2APOLBMMP12ALDH1A1 | |
| SCHEMBL12837317 | 0.84 | LMNA (0.76) | LMNAKMT2APOLBMMP12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251515-A | ANTITUMOR AGENTS, TREATMENT OF LEUKEMIA | SUAMI T | 1981-02-17 | — | — | US | disclosed |