Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14936748 | 0.88 | ABCB1 (0.52) | HCRTR1ABCB1TSHRMEN1KMT2A | |
| SCHEMBL30218361 | 0.87 | NPC1 (0.62) | ABCB1TSHRMEN1KMT2AMAPT | |
| SCHEMBL954173 | 0.87 | NPC1 (0.62) | ABCB1TSHRMEN1KMT2AMAPT | |
| SCHEMBL377080 | 0.87 | ABCB1 (0.61) | ABCB1MEN1KMT2AMAPTGAA | |
| SCHEMBL4431174 | 0.87 | ABCB1 (0.51) | HCRTR1ABCB1TSHRMEN1KMT2A | |
| SCHEMBL11627256 | 0.86 | HCRTR1 (0.47) | HCRTR1ABCB1TSHRMEN1KMT2A | |
| SCHEMBL3175398 | 0.83 | ABCB1 (0.48) | ABCB1TSHRMEN1KMT2AMAPT | |
| SCHEMBL7454665 | 0.83 | TSHR (0.60) | ABCB1TSHRMEN1KMT2AMAPT | |
| SCHEMBL17291051 | 0.82 | KDM4E (0.43) | ABCB1TSHRMEN1KMT2AMAPT | |
| SCHEMBL406193 | 0.81 | ERCC5 (0.59) | TSHRMEN1KMT2AGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558833-B | Pyrazole alcohol compound, pharmaceutical composition thereof and application thereof in medicines | 贵州医科大学 | 2022-03-04 | — | — | CN | disclosed |
| US-4248961-A | YELLOW COUPLER ACHIEVING GOOD COLOR DENSITY | CIBA-GEIGY AG (CH) | 1981-02-03 | — | — | US | disclosed |
| US-4179294-A | POLYMER MORDANT, ACIDIC PYRAZOLONE-CONTAINING OXONOL DYE, READILY DECOLORIZED BY IMMOBILIZATION | FUJI PHOTO FILM CO., LTD. (JP) | 1979-12-18 | — | — | US | disclosed |