Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.59 |
| ▸ | FEN1 | P39748 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3166061 | 0.85 | ERCC5 (0.62) | ERCC5FEN1MEN1KMT2ARAB9A | |
| SCHEMBL28674074 | 0.85 | HSD17B10 (0.54) | TSHRKMT2AALDH1A1RAB9AGAA | |
| SCHEMBL17861210 | 0.84 | TSHR (0.52) | ERCC5FEN1TSHRMEN1KMT2A | |
| SCHEMBL11772453 | 0.84 | NPC1 (0.53) | TSHRMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL32688037 | 0.84 | TSHR (0.52) | ERCC5FEN1TSHRMEN1KMT2A | |
| SCHEMBL31388602 | 0.84 | TSHR (0.72) | TSHRKMT2AALDH1A1L3MBTL1HSD17B10 | |
| SCHEMBL3949459 | 0.84 | CTNNB1 (0.54) | ERCC5FEN1TSHRMEN1KMT2A | |
| SCHEMBL11156928 | 0.83 | NLRP3 (0.47) | ERCC5FEN1TSHRALDH1A1RAB9A | |
| SCHEMBL6888758 | 0.83 | TSHR (0.50) | ERCC5FEN1TSHRMEN1KMT2A | |
| SCHEMBL290759 | 0.83 | F2R (0.51) | TSHRMEN1KMT2AALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112778133-A | high-pH-value chrome tanning auxiliary agent containing polyfunctional group structure and preparation method and application thereof | 南京工业大学 | 2021-05-11 | — | — | CN | claimed |
| EP-4741392-A1 | 1H-PYRAZOLO[4,3-C]PYRIDINE COMPOUND, AND COMPOSITION THEREOF AND USE THEREOF | Shenzhen TargetRx Co., Ltd. (CN) | 2026-05-13 | — | — | EP | disclosed |
| US-20250326732-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2025-10-23 | — | — | US | disclosed |
| US-20250090540-A1 | PI3K-ALPHA INHIBITORS AND METHODS OF USE THEREOF | RELAY THERAPEUTICS, INC. | 2025-03-20 | — | — | US | disclosed |
| WO-2025007863-A1 | 1H-PYRAZOLO[4,3-C]PYRIDINE COMPOUND, AND COMPOSITION THEREOF AND USE THEREOF | 深圳市塔吉瑞生物医药有限公司 | 2025-01-09 | — | — | WO | disclosed |
| CN-119241532-A | 1H-pyrazolo [4,3-c ] pyridine compound, composition and application thereof | 深圳市塔吉瑞生物医药有限公司 | 2025-01-03 | — | — | CN | disclosed |
| US-20240368106-A1 | HYDROXY AND ALKOXY COUMARINS AS MODULATORS OF POLRMT | PRETZEL THERAPEUTICS, INC. (US) | 2024-11-07 | — | — | US | disclosed |
| EP-4399196-A1 | PI3K-ALPHA INHIBITORS AND METHODS OF USE THEREOF | Relay Therapeutics, Inc. (US) | 2024-07-17 | — | — | EP | disclosed |
| CN-118201896-A | PI 3K-alpha inhibitors and methods of use thereof | 传达治疗有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-116751199-A | Mitochondrial protease targeted chimera, preparation method and application | 中国科学院基础医学与肿瘤研究所(筹) | 2023-09-15 | — | — | CN | disclosed |
| US-20070054906-A1 | Novel pyrazolopyrimidines as cyclin dependent kinase inhibitors | SCHERING CORPORATION | 2007-03-08 | — | — | US | disclosed |
| US-20070037824-A1 | Enzyme inhibitors from pyrazolo[1,5a]pyrimidine as enzyme inhibitors | SCHERING CORPORATION | 2007-02-15 | — | — | US | disclosed |
| US-20070037824-A1 | Enzyme inhibitors from pyrazolo[1,5a]pyrimidine as enzyme inhibitors | SCHERING CORPORATION | 2007-02-15 | — | — | US | disclosed |
| US-7161003-B1 | Pyrazolopyrimidines as cyclin dependent kinase inhibitors | SCHERING CORPORATION (US) | 2007-01-09 | — | — | US | disclosed |
| US-7161003-B1 | Pyrazolopyrimidines as cyclin dependent kinase inhibitors | SCHERING CORPORATION (US) | 2007-01-09 | — | — | US | disclosed |
| CN-1152305-A | Substituted 3-phenylpyrazoles as herbicides | BASF AG (DE) | 1997-06-18 | — | — | CN | disclosed |
| EP-0761658-A1 | Azole-phenyl urea derivatives as ACAT inhibitors and their production | NIHON NOHYAKU CO., LTD. (JP) | 1997-03-12 | — | — | EP | disclosed |
| CN-1058406-A | The pyrroles who replaces, its preparation method and application thereof | HOECHST AG (DE) | 1992-02-05 | — | — | CN | disclosed |
| US-4020073-A | Process for O-acylating thallus salts of 2-pyridone | TAYLOR EDWARD C | 1977-04-26 | — | — | US | disclosed |
| US-3947488-A | O-Acylation using organothallium compounds | TAYLOR EDWARD C | 1976-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250326732-A1 | CHROMEN-2-ONE MODULATORS OF POLRMT | POLRMT, TFAM, POLM | ERCC5 2287/4885FEN1 320/4885TSHR 2586/4885 |
| US-20070037824-A1 | Enzyme inhibitors from pyrazolo[1,5a]pyrimidine as enzyme inhibitors | CDK2, CDK5, CDKN1A | ERCC5 643/4885FEN1 131/4885TSHR 4071/4885 |
| US-20070054906-A1 | Novel pyrazolopyrimidines as cyclin dependent kinase inhibitors | CDK2, CDK1, CDKN1A | ERCC5 1043/4885FEN1 697/4885TSHR 3857/4885 |
| US-20250090540-A1 | PI3K-ALPHA INHIBITORS AND METHODS OF USE THEREOF | PIK3CA, PIK3CB, PIK3CD | ERCC5 2967/4885FEN1 1632/4885TSHR 4407/4885 |
| US-20240368106-A1 | HYDROXY AND ALKOXY COUMARINS AS MODULATORS OF POLRMT | POLRMT, ACAT1, TFAM | ERCC5 1972/4885FEN1 1134/4885TSHR 4379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.