SCHEMBL11339705

SCHEMBL11339705

C/C=C(\C)C(=O)OCc1ccco1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.68
TDP1 Q9NUW8 3/20 0.47
MAPK1 P28482 2/20 0.47
MAPT P10636 3/20 0.46
NPSR1 Q6W5P4 2/20 0.46
LMNA P02545 2/20 0.46
TP53 P04637 1/20 0.46
HTT P42858 1/20 0.46
POLB P06746 5/20 0.45
TSHR P16473 2/20 0.45
CYP2D6 P10635 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
RECQL P46063 1/20 0.43
RAB9A P51151 1/20 0.43
SLC1A3 P43003 1/20 0.42
SLC1A2 P43004 1/20 0.42
SLC1A1 P43005 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10602301 1.00 ALDH1A1 (0.68) ALDH1A1TDP1MAPK1MAPTNPSR1
SCHEMBL6871220 1.00 ALDH1A1 (0.68) ALDH1A1TDP1MAPK1MAPTNPSR1
SCHEMBL27438885 0.89 ALDH1A1 (0.66) ALDH1A1TDP1MAPK1MAPTNPSR1
SCHEMBL28668850 0.83 ALDH1A1 (0.57) ALDH1A1TDP1MAPK1MAPTNPSR1
SCHEMBL11583754 0.82 ALDH1A1 (0.70) ALDH1A1TDP1MAPK1MAPTNPSR1
SCHEMBL36525 0.82 ALDH1A1 (0.70) ALDH1A1TDP1MAPK1MAPTNPSR1
SCHEMBL28514816 0.82 ALDH1A1 (0.56) ALDH1A1TDP1MAPK1MAPTNPSR1
SCHEMBL190434 0.81 ALDH1A1 (1.00) ALDH1A1TDP1MAPK1MAPTNPSR1
SCHEMBL12394480 0.81 ALDH1A1 (0.68) ALDH1A1TDP1MAPK1MAPTNPSR1
SCHEMBL14934951 0.81 ALDH1A1 (0.68) ALDH1A1TDP1MAPK1MAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3978241-A FURAN ESTER COMPOUNDS FIRMENICH & CIE (CH) 1976-08-31 US claimed
US-4303689-A Flavoring with pyrazine derivatives FIRMENICH SA (CH) 1981-12-01 US disclosed
US-4138410-A Flavoring agent FIRMENICH & CIE (CH) 1979-02-06 US disclosed
US-4126618-A FLAVOR ADDITIVES FOR FOODS AND BEVERAGES FIRMENICH & CIE (CH) 1978-11-21 US disclosed
US-4085109-A Pyridine sulfur flavoring agents FIRMENICH & CIE (CH) 1978-04-18 US disclosed
US-3989713-A Pyrrylmethylthio flavoring agents FIRMENICH & CIE (CH) 1976-11-02 US disclosed
US-3952024-A FLAVOR ADDITIVE FOR FOODS AND BEVERAGES FIRMENICH & CIE (CH) 1976-04-20 US disclosed
US-3943260-A TETRAHYDRO-THIO-PHEN-3-ONES FIRMENICH & CIE (CH) 1976-03-09 US disclosed
US-3931246-A FURYLALKYL-THIOETHERS FIRMENICH & CIE (CH) 1976-01-06 US disclosed
US-3931245-A FURYLALKYLTHIOL CARBOXYLATES FIRMENICH & CIE (CH) 1976-01-06 US disclosed