Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL36525 | 0.89 | ALDH1A1 (0.70) | ALDH1A1TDP1MAPK1MAPTNPSR1 | |
| SCHEMBL19450492 | 0.88 | ALDH1A1 (0.59) | ALDH1A1TDP1MAPK1MAPTNPSR1 | |
| SCHEMBL28657462 | 0.87 | ALDH1A1 (0.68) | ALDH1A1TDP1MAPK1MAPTNPSR1 | |
| Methacrylic Acid SCHEMBL28728201 | 0.84 | ALDH1A1 (0.64) | ALDH1A1TDP1MAPK1MAPTNPSR1 | |
| SCHEMBL29056404 | 0.83 | ALDH1A1 (0.62) | ALDH1A1TDP1MAPK1MAPTNPSR1 | |
| SCHEMBL18918951 | 0.83 | ALDH1A1 (0.62) | ALDH1A1TDP1MAPK1MAPTNPSR1 | |
| SCHEMBL28959430 | 0.83 | ALDH1A1 (0.61) | ALDH1A1TDP1MAPK1MAPTNPSR1 | |
| SCHEMBL11583754 | 0.82 | ALDH1A1 (0.70) | ALDH1A1TDP1MAPK1MAPTNPSR1 | |
| SCHEMBL4894662 | 0.81 | ALDH1A1 (0.68) | ALDH1A1TDP1MAPK1MAPTNPSR1 | |
| SCHEMBL190434 | 0.81 | ALDH1A1 (1.00) | ALDH1A1TDP1MAPK1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190315892-A1 | POLYMERS INCLUDING A METHYLENE BETA-KETOESTER AND PRODUCTS FORMED THEREFROM | SIRRUS, INC. | 2019-10-17 | — | — | US | disclosed |
| US-10414839-B2 | Polymers including a methylene beta-ketoester and products formed therefrom | SIRRUS, INC. (US) | 2019-09-17 | — | — | US | disclosed |
| EP-3293216-A1 | POLYMERS FORMED FROM METHYLENE BETA-KETOESTER MONOMERS AND PRODUCTS FORMED THEREFROM | Sirrus, Inc. (US) | 2018-03-14 | — | — | EP | disclosed |
| US-20170355789-A1 | POLYMERS INCLUDING A METHYLENE BETA-KETOESTER AND PRODUCTS FORMED THEREFROM | SIRRUS, INC. | 2017-12-14 | — | — | US | disclosed |
| US-20170355789-A1 | POLYMERS INCLUDING A METHYLENE BETA-KETOESTER AND PRODUCTS FORMED THEREFROM | SIRRUS, INC. | 2017-12-14 | — | — | US | disclosed |
| EP-2768872-B1 | METHODS FOR MAKING METHYLENE BETA-KETOESTER MONOMERS | SIRRUS INC (US) | 2017-11-22 | — | — | EP | disclosed |
| US-20170073438-A1 | POLYMERS INCLUDING A METHYLENE BETA-KETOESTER AND PRODUCTS FORMED THEREFROM | SIRRUS, INC. | 2017-03-16 | — | — | US | disclosed |
| US-20170073438-A1 | POLYMERS INCLUDING A METHYLENE BETA-KETOESTER AND PRODUCTS FORMED THEREFROM | SIRRUS, INC. | 2017-03-16 | — | — | US | disclosed |
| US-9527795-B2 | Methylene beta-ketoester monomers, methods for making methylene beta-ketoester monomers, polymerizable compositions and products formed therefrom | SIRRUS, INC. (US) | 2016-12-27 | — | — | US | disclosed |
| US-9527795-B2 | Methylene beta-ketoester monomers, methods for making methylene beta-ketoester monomers, polymerizable compositions and products formed therefrom | SIRRUS, INC. (US) | 2016-12-27 | — | — | US | disclosed |
| US-20140288230-A1 | METHYLENE BETA-KETOESTER MONOMERS, METHODS FOR MAKING METHYLENE BETA-KETOESTER MONOMERS, POLYMERIZABLE COMPOSITIONS AND PRODUCTS FORMED THEREFROM | SIRRUS, INC. | 2014-09-25 | — | — | US | disclosed |
| US-20140288230-A1 | METHYLENE BETA-KETOESTER MONOMERS, METHODS FOR MAKING METHYLENE BETA-KETOESTER MONOMERS, POLYMERIZABLE COMPOSITIONS AND PRODUCTS FORMED THEREFROM | SIRRUS, INC. | 2014-09-25 | — | — | US | disclosed |
| WO-2013066629-A1 | METHYLENE BETA-KETOESTER MONOMERS, METHODS FOR MAKING METHYLENE BETA-KETOESTER MONOMERS, POLYMERIZABLE COMPOSITIONS AND PRODUCTS FORMED THEREFROM | BIOFORMIX, LLC (US) | 2013-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140288230-A1 | METHYLENE BETA-KETOESTER MONOMERS, METHODS FOR MAKING METHYLENE BETA-KETOESTER MONOMERS, POLYMERIZABLE COMPOSITIONS AND PRODUCTS FORMED THEREFROM | MACF1, MSMO1, ILK | ALDH1A1 1292/4885TDP1 2962/4885MAPK1 3325/4885 |
| US-20170355789-A1 | POLYMERS INCLUDING A METHYLENE BETA-KETOESTER AND PRODUCTS FORMED THEREFROM | BHMT2, BHMT, MACF1 | ALDH1A1 562/4885TDP1 1745/4885MAPK1 1437/4885 |
| US-10414839-B2 | Polymers including a methylene beta-ketoester and products formed therefrom | BHMT2, BHMT, MACF1 | ALDH1A1 562/4885TDP1 1745/4885MAPK1 1437/4885 |
| US-20190315892-A1 | POLYMERS INCLUDING A METHYLENE BETA-KETOESTER AND PRODUCTS FORMED THEREFROM | BHMT2, MACF1, BHMT | ALDH1A1 426/4885TDP1 1384/4885MAPK1 1453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.