Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 7/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5251085 | 0.80 | HSPA5 (0.40) | LMNAIDO1TSHRPNMTTAAR1 | |
| SCHEMBL10888499 | 0.78 | APOBEC3G (0.44) | LMNARAB9AIDO1TSHRPNMT | |
| SCHEMBL10457917 | 0.78 | TSHR (0.39) | LMNAIDO1TSHRPNMTTAAR1 | |
| SCHEMBL9479489 | 0.76 | ALDH1A1 (0.44) | IDO1TSHRTDP1CYP3A4ALDH1A1 | |
| SCHEMBL43012 | 0.76 | IDO1 (0.59) | IDO1TDP1ALDH1A1KDM4EATM | |
| SCHEMBL5249460 | 0.76 | TSHR (0.35) | LMNAIDO1TSHRPNMTTAAR1 | |
| SCHEMBL18243840 | 0.76 | TSHR (0.35) | SMN1; SMN2RAB9AIDO1TSHRPNMT | |
| SCHEMBL8522980 | 0.76 | GABRA1 (0.42) | LMNAKCNH2ALDH1A1KDM4E | |
| SCHEMBL18242672 | 0.73 | TAAR1 (0.34) | IDO1TSHRPNMTTAAR1 | |
| SCHEMBL2095076 | 0.73 | IDO1 (0.41) | IDO1TDP1ALDH1A1KDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4268510-A | DEMETHANIZATION, METABOLISM, RUMEN | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-05-19 | — | — | US | claimed |