Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11340332 | 1.00 | TSHR (0.44) | TSHRALDH1A1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL4038148 | 0.79 | TSHR (0.47) | TSHRALDH1A1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL7253286 | 0.79 | TSHR (0.47) | TSHRALDH1A1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL23327133 | 0.74 | TSHR (0.42) | TSHRALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL11344985 | 0.73 | ALDH1A1 (0.50) | TSHRALDH1A1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL29210356 | 0.72 | TSHR (0.58) | TSHRALDH1A1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL42755 | 0.71 | — | — | |
| Ammonia Solution, Strong SCHEMBL28649186 | 0.69 | — | — | |
| SCHEMBL1505728 | 0.69 | — | — | |
| SCHEMBL10010574 | 0.69 | TSHR (0.67) | TSHRALDH1A1RAB9ASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4305859-A | THERMOSETTING ENAMELS | CANADIAN INDUSTRIES LIMITED (CA) | 1981-12-15 | — | — | US | disclosed |