Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28331986 | 0.78 | CYP1A2 (0.64) | ADRB2ADRB1ADRB3KDM4ECYP1A2 | |
| SCHEMBL1496780 | 0.77 | SCN4A (0.65) | IDO1ADRB2ADRB1ADRB3KDM4E | |
| SCHEMBL15954437 | 0.77 | LMNA (0.62) | IDO1ADRB2KDM4ECYP1A2MEN1 | |
| SCHEMBL11324282 | 0.77 | CYP1A2 (0.50) | ADRB2ADRB1ADRB3KDM4ECYP1A2 | |
| SCHEMBL10635891 | 0.77 | IDO1 (0.51) | IDO1KDM4ECYP1A2CYP2C19LMNA | |
| SCHEMBL10635975 | 0.77 | IDO1 (0.51) | IDO1KDM4ECYP1A2MEN1CYP2C19 | |
| SCHEMBL1496631 | 0.77 | KMT2A (0.51) | IDO1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL2355180 | 0.77 | ADRB2 (0.44) | ADRB2ADRB1ADRB3KDM4ECYP1A2 | |
| SCHEMBL1496496 | 0.74 | LMNA (0.61) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL30987975 | 0.74 | LMNA (0.61) | ADRB2ADRB1ADRB3KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4255152-A | USING A DISPERSE DYE, WATER, AND AN ADDUCT OF ETHYLENE, PROPYLENE, OR STYRENE OXIDE AND A CYCLIC-SUBSTITUTED PHENOL; LEVELLING | CIBA-GEIGY CORPORATION (US) | 1981-03-10 | — | — | US | disclosed |