Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18508393 | 0.80 | MAPT (0.52) | ALDH1A1KDM4EMAPTRAB9AKMT2A | |
| SCHEMBL20402746 | 0.80 | MAPT (0.52) | ALDH1A1KDM4EMAPTRAB9AKMT2A | |
| SCHEMBL2323024 | 0.78 | ALDH1A1 (0.63) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL31582428 | 0.78 | ALDH1A1 (0.63) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL19454785 | 0.75 | TDP1 (0.61) | ALDH1A1KDM4EGAAHPGDMAPT | |
| SCHEMBL11126066 | 0.75 | MAPT (0.61) | ALDH1A1KDM4EGAAMAPTRAB9A | |
| SCHEMBL10815415 | 0.74 | ALDH1A1 (0.55) | ALDH1A1KDM4EGAAHPGDGLA | |
| SCHEMBL12015941 | 0.73 | MAPT (0.51) | ALDH1A1KDM4EGAAHPGDMAPT | |
| SCHEMBL11264204 | 0.72 | MAPT (0.50) | ALDH1A1KDM4EGAAHPGDMAPT | |
| SCHEMBL16301332 | 0.72 | ALDH1A1 (0.49) | ALDH1A1KDM4EGAAHPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251527-A | ANTIINFLAMMATORY AGENTS | DIAMOND SHAMROCK CORPORATION (US) | 1981-02-17 | — | — | US | disclosed |