Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6995462 | 0.78 | MAPT (0.46) | KDM4EMEN1ALDH1A1POLBMAPT | |
| SCHEMBL10437588 | 0.68 | KDM4E (0.31) | KDM4EMEN1USP2ALDH1A1POLB | |
| SCHEMBL3205689 | 0.66 | MEN1 (0.34) | KDM4EMEN1USP2ALDH1A1POLB | |
| SCHEMBL30335572 | 0.63 | MAPT (0.50) | KDM4EMEN1USP2ALDH1A1POLB | |
| SCHEMBL29463681 | 0.63 | MAPT (0.50) | KDM4EMEN1USP2ALDH1A1POLB | |
| SCHEMBL87693 | 0.63 | MAPT (0.50) | KDM4EMEN1USP2ALDH1A1POLB | |
| SCHEMBL30716827 | 0.61 | MAPT (0.48) | KDM4EMEN1USP2ALDH1A1POLB | |
| SCHEMBL5767894 | 0.57 | ADRA2A (0.39) | KDM4EMEN1USP2ALDH1A1POLB | |
| SCHEMBL1326949 | 0.57 | — | — | |
| SCHEMBL28650137 | 0.56 | CA2 (0.42) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003016-B1 | PYRAZINO-BENZOXAZEPINE AND -BENZTHIAZEPINE DERIVATIVES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANDOZ AG (CH) | 1981-12-30 | — | — | EP | disclosed |
| EP-0003016-B1 | PYRAZINO-BENZOXAZEPINE AND -BENZTHIAZEPINE DERIVATIVES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANDOZ AG (CH) | 1981-12-30 | — | — | EP | disclosed |
| EP-0003016-A1 | Pyrazino-benzoxazepine and -benzthiazepine derivatives, processes for their production and pharmaceutical compositions containing them | SANDOZ AG (CH) | 1979-07-25 | — | — | EP | disclosed |