Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4965995 | 0.77 | — | — | |
| Ammonia Solution, Strong SCHEMBL27522184 | 0.77 | — | — | |
| SCHEMBL2057453 | 0.73 | — | — | |
| SCHEMBL11801776 | 0.73 | ALDH1A1 (0.35) | — | |
| SCHEMBL28009309 | 0.67 | LMNA (0.41) | TSHRNFKB1LMNACYP1A2MAOA | |
| SCHEMBL5409424 | 0.65 | — | — | |
| SCHEMBL33749 | 0.65 | LMNA (0.47) | TSHRNFKB1LMNACYP1A2MAOA | |
| Water SCHEMBL6817829 | 0.62 | LMNA (0.44) | TSHRNFKB1LMNACYP1A2MAOA | |
| SCHEMBL11150248 | 0.62 | — | — | |
| SCHEMBL124579 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102781230-A | Formulations and uses thereof | BASF SE | 2012-11-14 | — | — | CN | disclosed |
| US-4285738-A | A HYPERTONIC SOLUTION OF UREA OR AN ACID SALT OF GUANIDINE, A SULFUR-CONTAINING REDUCING AGENT, AND A PROTEOLYTIC ENZYME; SYNERGISTIC | SENJU PHARMACEUTICAL CO., LTD. (JP) | 1981-08-25 | — | — | US | disclosed |