Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3529060 | 0.80 | MAPT (0.82) | NPSR1KDM4ERXFP1MAPTMEN1 | |
| SCHEMBL8804658 | 0.79 | KDM4E (0.82) | NPSR1KDM4ERXFP1MAPTMEN1 | |
| SCHEMBL9362200 | 0.78 | HDAC1 (0.68) | NPSR1KDM4ERXFP1MAPTMEN1 | |
| SCHEMBL3783679 | 0.77 | GRM4 (0.79) | NPSR1KDM4ERXFP1MAPTMEN1 | |
| SCHEMBL3528846 | 0.77 | NPSR1 (0.61) | NPSR1KDM4ERXFP1MAPTMEN1 | |
| SCHEMBL24252964 | 0.76 | MAPT (0.66) | NPSR1KDM4ERXFP1MAPTMEN1 | |
| SCHEMBL28197181 | 0.76 | RAB9A (0.70) | NPSR1KDM4ERXFP1MAPTMEN1 | |
| SCHEMBL8980369 | 0.76 | KCNK3 (0.69) | MAPTMEN1KMT2ASMN1; SMN2HDAC1 | |
| SCHEMBL866785 | 0.75 | MAPT (0.78) | NPSR1KDM4ERXFP1MAPTMEN1 | |
| SCHEMBL30492552 | 0.75 | MAPT (0.78) | NPSR1KDM4ERXFP1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0010030-B1 | DERIVATIVES OF 2'-(ORTHO-CHLORO-BENZOYL),4'-CHLORO-GLYCIN ANILIDE, THEIR PREPARATION AND THEIR USE IN MEDICINES | PIERRE FABRE S.A. (FR) | 1982-05-05 | — | — | EP | claimed |
| EP-0010030-A1 | Derivatives of 2'-(ortho-chloro-benzoyl),4'-chloro-glycin anilide, their preparation and their use in medicines | PIERRE FABRE S.A. (FR) | 1980-04-16 | — | — | EP | claimed |
| EP-0044091-A2 | Process for the preparation of N-alkylamino-benzophenones | PIERRE FABRE S.A. (FR) | 1982-01-20 | — | — | EP | disclosed |
| EP-0010030-A1 | Derivatives of 2'-(ortho-chloro-benzoyl),4'-chloro-glycin anilide, their preparation and their use in medicines | PIERRE FABRE S.A. (FR) | 1980-04-16 | — | — | EP | disclosed |