SCHEMBL1134084

SCHEMBL1134084

COc1cccc(CN(C)Cc2cccc(OC)c2)c1

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.61
CALM1 P0DP23 1/20 0.59
CAMKK2 Q96RR4 1/20 0.59
AOC3 Q16853 1/20 0.59
ACHE P22303 2/20 0.57
BCHE P06276 1/20 0.57
TAAR1 Q96RJ0 3/20 0.56
IDO1 P14902 2/20 0.56
AGXT P21549 2/20 0.56
MEN1 O00255 2/20 0.56
ALDH1A1 P00352 1/20 0.53
CHRM2 P08172 1/20 0.53
CHRM1 P11229 1/20 0.53
CHRM3 P20309 1/20 0.53
HSD17B2 P37059 1/20 0.52
CMA1 P23946 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30093216 0.96 CALM1 (0.60) KMT2ACALM1CAMKK2AOC3ACHE
SCHEMBL9416597 0.93 ACHE (0.59) KMT2ACALM1CAMKK2AOC3ACHE
SCHEMBL4526554 0.91 CALM1 (0.55) KMT2ACALM1CAMKK2AOC3ACHE
SCHEMBL20609081 0.88 KMT2A (0.55) KMT2ACALM1CAMKK2AOC3ACHE
SCHEMBL29547354 0.88 CALM1 (0.64) KMT2ACALM1CAMKK2AOC3ACHE
SCHEMBL850832 0.88 CALM1 (0.64) KMT2ACALM1CAMKK2AOC3ACHE
SCHEMBL15308564 0.88 BCHE (0.58) KMT2ACALM1CAMKK2AOC3ACHE
SCHEMBL23374687 0.86 TAAR1 (0.54) KMT2ACALM1CAMKK2AOC3ACHE
SCHEMBL15790970 0.86 BCHE (0.56) KMT2ACALM1CAMKK2AOC3ACHE
SCHEMBL12992872 0.86 BCHE (0.60) KMT2ACALM1CAMKK2AOC3ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2285339-B1 INITIATOR SYSTEM CONTAINING A DIARYLAKYLAMINE DERIVATIVE, HARDENABLE COMPOSITION AND USE THEREOF 3M INNOVATIVE PROPERTIES CO (US) 2012-12-19 EP disclosed
US-8314162-B2 Initiator system containing a diarylalkylamine derivate, hardenable composition and use thereof 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-11-20 US disclosed
US-20110077361-A1 INITIATOR SYSTEM CONTAINING A DIARYLALKYLAMINE DERIVATE, HARDENABLE COMPOSITION AND USE THEREOF SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2011-03-31 US disclosed
EP-2285339-A1 INITIATOR SYSTEM CONTAINING A DIARYLAKYLAMINE DERIVATIVE, HARDENABLE COMPOSITION AND USE THEREOF 3M Innovative Properties Company (US) 2011-02-23 EP disclosed
WO-2009151957-A1 INITIATOR SYSTEM CONTAINING A DIARYLAKYLAMINE DERIVATIVE, HARDENABLE COMPOSITION AND USE THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-12-17 WO disclosed
EP-2133064-A1 Initiator system containing a diarylalkylamine derivate, hardenable composition and use thereof 3M Innovative Properties Company (US) 2009-12-16 EP disclosed
EP-0613879-A1 PHELLODENDRINE ANALOGS AND ALLERGY TYPE IV SUPPRESSOR CONTAINING THE SAME AS ACTIVE INGREDIENT TSUMURA & CO. (JP) 1994-09-07 EP disclosed