Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | PTPRB | P23467 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11347525 | 0.85 | LMNA (0.51) | LMNAAPEX1CYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL9816334 | 0.85 | LMNA (0.53) | LMNAAPEX1HIF1ASMN1; SMN2L3MBTL1 | |
| Metrizoic Acid SCHEMBL29570734 | 0.82 | LMNA (0.52) | LMNASMN1; SMN2 | |
| Metrizoic Acid SCHEMBL37641 | 0.82 | LMNA (0.52) | LMNASMN1; SMN2 | |
| SCHEMBL11344450 | 0.82 | APEX1 (0.39) | LMNAAPEX1CYP2C19HIF1AL3MBTL1 | |
| Metrizoic Acid SCHEMBL1237887 | 0.81 | LMNA (0.51) | LMNASMN1; SMN2 | |
| Metrizoic Acid SCHEMBL1236887 | 0.81 | LMNA (0.51) | LMNASMN1; SMN2 | |
| SCHEMBL11700573 | 0.81 | LMNA (0.58) | LMNAAPEX1CYP2C19SMN1; SMN2L3MBTL1 | |
| SCHEMBL11694200 | 0.80 | LMNA (0.47) | LMNAAPEX1CYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL11690984 | 0.80 | LMNA (0.47) | LMNAAPEX1CYP2C19HIF1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4307072-A | X-RAY CONTRAST AGENTS | MALLINCKRODT, INC. (US) | 1981-12-22 | — | — | US | disclosed |