Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PTPRB | P23467 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11347525 | 0.97 | LMNA (0.51) | LMNAAPEX1SMN1; SMN2L3MBTL1EGLN1 | |
| SCHEMBL11700573 | 0.92 | LMNA (0.58) | LMNAAPEX1SMN1; SMN2L3MBTL1EGLN1 | |
| SCHEMBL11464143 | 0.91 | LMNA (0.45) | LMNAAPEX1SMN1; SMN2L3MBTL1EGLN1 | |
| SCHEMBL11694200 | 0.91 | LMNA (0.47) | LMNAAPEX1SMN1; SMN2L3MBTL1EGLN1 | |
| SCHEMBL11690984 | 0.91 | LMNA (0.47) | LMNAAPEX1SMN1; SMN2L3MBTL1EGLN1 | |
| SCHEMBL11346928 | 0.90 | LMNA (0.46) | LMNAAPEX1SMN1; SMN2L3MBTL1EGLN1 | |
| SCHEMBL11696569 | 0.86 | LMNA (0.43) | LMNAAPEX1SMN1; SMN2L3MBTL1EGLN1 | |
| SCHEMBL11340965 | 0.85 | LMNA (0.53) | LMNAAPEX1SMN1; SMN2L3MBTL1EGLN1 | |
| SCHEMBL9563844 | 0.84 | LMNA (0.58) | LMNASMN1; SMN2POLBKDM4EHIF1A | |
| SCHEMBL10877845 | 0.84 | LMNA (0.50) | LMNASMN1; SMN2L3MBTL1HPGDPTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153992-B1 | WATER SOLUBLE DERIVATIVES OF 3,5-DIACETO AMIDO-2,4,6-TRIIODOBENZOIC ACID AND PROCESS FOR THEIR PREPARATION AND USE | Dr. Franz Köhler Chemie GmbH (DE) | 1991-10-16 | — | — | EP | claimed |
| EP-0153992-A2 | Water soluble derivatives of 3,5-diaceto amido-2,4,6-triiodobenzoic acid and process for their preparation and use | Dr. Franz Köhler Chemie GmbH (DE) | 1985-09-11 | — | — | EP | disclosed |