SCHEMBL11342

SCHEMBL11342

CC(C)c1ccc(-c2ccccc2)c(C(C)C)c1C(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
GABRA1 P14867 2/20 0.35
GABRB2 P47870 1/20 0.35
CDC25A P30304 1/20 0.35
CDC25B P30305 1/20 0.35
HSP90AA1 P07900 1/20 0.35
ESR2 Q92731 1/20 0.34
PTGS1 P23219 3/20 0.34
MEN1 O00255 2/20 0.34
PTGS2 P35354 2/20 0.34
KMT2A Q03164 2/20 0.34
FABP2 P12104 1/20 0.34
TSHR P16473 1/20 0.34
AKR1C4 P17516 1/20 0.34
ADRA2B P18089 1/20 0.34
CHRM3 P20309 1/20 0.34
HTR2C P28335 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29367513 1.00 CA12 (0.36) CA12CA1CA2CA9GABRA1
SCHEMBL15608644 0.98 CA12 (0.35) CA12CA1CA2CA9GABRA1
Ammonia Solution, Strong SCHEMBL28410562 0.98 CA12 (0.35) CA12CA1CA2CA9GABRA1
Hydrochloric Acid SCHEMBL15609201 0.96 CA12 (0.34) CA12CA1CA2CA9GABRA1
SCHEMBL11513836 0.96 CA12 (0.38) CA12CA1CA2CA9MEN1
SCHEMBL15609202 0.94 CA12 (0.33) CA12CA1CA2CA9GABRA1
Phosphoric Acid SCHEMBL3912754 0.89 PTPN5 (0.38) CA12CA1CA2CA9PTGS1
SCHEMBL6838848 0.89 CDC25A (0.41) CDC25ACDC25BESR2PTGS1MEN1
SCHEMBL11326459 0.87 MEN1 (0.37) HSP90AA1MEN1KMT2ALMNAMAPT
SCHEMBL8135460 0.84 GCGR (0.35) CA12CA1CA2CA9GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1899 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115850254-B Synthesis method of pyrifos 山东润博生物科技有限公司 2024-06-25 CN claimed
EP-4359401-A1 PROCESS FOR PREPARING EGFR INHIBITORS Blueprint Medicines Corporation (US) 2024-05-01 EP claimed
CN-117430552-A Near infrared two-region fluorescent dye molecule diphenylamine acridine and preparation method and application thereof 复旦大学 2024-01-23 CN claimed
CN-117384129-A Impurity compound, preparation method and application thereof 浙江九洲药业股份有限公司 2024-01-12 CN claimed
CN-116724021-A Synthesis of polyfluorinated aryl and heteroaryl carboxamides 巴斯夫欧洲公司 2023-09-08 CN claimed
CN-116470045-A Nitrogen-containing conjugated lignin lithium-sulfur battery positive electrode material and preparation method thereof 东北林业大学 2023-07-21 CN claimed
WO-2022271801-A1 PROCESS FOR PREPARING EGFR INHIBITORS BLUEPRINT MEDICINES CORPORATION (US) 2022-12-29 WO claimed
CN-115093547-A Bicarbazole polymer p-BCz-Ph and synthetic method and application thereof 中盐金坛盐化有限责任公司 2022-09-23 CN claimed
CN-115052855-A Preparation method of amide compound, crystal form and salt thereof 昊运股份有限公司 2022-09-13 CN claimed
CN-110372524-B Triphenylamine organic hole transport material with binaphthyl amine as mother core, and synthesis and application thereof 天津理工大学 2022-08-30 CN claimed
US-20090042945-A1 Benzo[d]isoxazol-3-yl-amine Compounds and Their Use as Vanilloid Receptor Ligands GRUENENTHAL GMBH (DE) 2009-02-12 US claimed
US-5847040-A Lower alkyl biphenyls as plasticizers for polyurethane KOCH INDUSTRIES, INC. (US) 1998-12-08 US claimed
US-5696184-A EPOXY POLYMER CONTAINING DIISOPROPYLBIPHENYL AND/OR TRIISOPROPYLBIPHENYL; INCREASED FLEXIBILITY AND TOUGHNESS KOCH INDUSTRIES, INC. (US) 1997-12-09 US claimed
EP-0601690-B1 Solvent for use in carbonless paper, comprising diisopropylbiphenyl and triisopropylbiphenyl, and products utilising the same KOCH IND INC (US) 1997-04-23 EP claimed
US-5489646-A CAN USE HIGH LOAD LEVELS KOCH INDUSTRIES, INC. (US) 1996-02-06 US claimed
US-5458974-A Low odor carbonless paper solvent KOCH INDUSTRIES, INC. (US) 1995-10-17 US claimed
EP-0671124-A1 Solid biocidal concentrates ROHM AND HAAS COMPANY (US) 1995-09-13 EP claimed
US-5430046-A Containing a melting point depressant which is miscible; repeatedly meltable, solidifiable ROHM AND HAAS COMPANY (US) 1995-07-04 US claimed
EP-0601690-A1 Solvent for use in carbonless paper, comprising diisopropylbiphenyl and triisopropylbiphenyl, and products utilising the same KOCH INDUSTRIES, INC. (US) 1994-06-15 EP claimed
US-5318940-A Writing or printing recording sheet with coating having microcapsules containing chromogen and odorless solvent KOCH INDUSTRIES, INC. (US) 1994-06-07 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090042945-A1 Benzo[d]isoxazol-3-yl-amine Compounds and Their Use as Vanilloid Receptor Ligands TRPV1, TRPV3, TRPV5 CA12 2549/4885CA1 3307/4885CA2 753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.